NOS2/iNOS Antibody (C-11): sc-7271
- NOS2/iNOS Antibody (C-11) is a mouse monoclonal IgG1 κ NOS2/iNOS antibody, cited in 637 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1126-1144 near the C-terminus of NOS2 of mouse origin
- NOS2/iNOS Antibody (C-11) is recommended for detection of NOS2 (iNOS) of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA
- Anti-NOS2/iNOS Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to either TRITC or Alexa Fluor® 405 for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NOS2/iNOS Antibody (C-11) for WB and IHC(P) applications. These reagents are now offered in bundles with NOS2/iNOS Antibody (C-11) (see ordering information below).
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NOS2 Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Nitric Oxide Synthase 2 (NOS2), also known as inducible Nitric Oxide Synthase (iNOS) or NOS2A. NOS2 mouse monoclonal antibody (C-11) targets an epitope mapping between amino acids 1126-1144 near the C-terminus of the mouse NOS2 protein, ensuring precise binding and reliable detection. NOS2 is a critical enzyme responsible for the synthesis of nitric oxide (NO), a versatile signaling molecule involved in various biological processes such as immune response, inflammation, and neurotransmission. The function of NOS2 is particularly important in host defense mechanisms, where NOS2 produces large quantities of NO to eliminate pathogens, as well as in the regulation of inflammatory pathways. NOS2 mouse monoclonal antibody (C-11) exhibits broad species reactivity, recognizing NOS2 from mouse, rat, and human origins, and is recommended for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Additionally, NOS2 monoclonal antibody (C-11) is available in both non-conjugated and various conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing flexibility for diverse experimental setups. NOS2 antibody (C-11) is recommended for researchers investigating the role of nitric oxide in health and disease, contributing to advancements in understanding inflammatory responses and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NOS2/iNOS Antibody (C-11) References:
- Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis. | Heiss, LN., et al. 1994. Proc Natl Acad Sci U S A. 91: 267-70. PMID: 7506415
- Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. | Kamijo, R., et al. 1994. Science. 263: 1612-5. PMID: 7510419
- Nitric oxide synthases: roles, tolls, and controls. | Nathan, C. and Xie, QW. 1994. Cell. 78: 915-8. PMID: 7522969
- Nitric oxide synthase: aspects concerning structure and catalysis. | Marletta, MA. 1994. Cell. 78: 927-30. PMID: 7522970
- Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. | Bukrinsky, MI., et al. 1995. J Exp Med. 181: 735-45. PMID: 7530762
- NO at work. | Schmidt, HH. and Walter, U. 1994. Cell. 78: 919-25. PMID: 7923361
- Nitric oxide is an important mediator for tumoricidal activity in vivo. | Farias-Eisner, R., et al. 1994. Proc Natl Acad Sci U S A. 91: 9407-11. PMID: 7937779
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NOS2/iNOS Antibody (C-11) | sc-7271 | 200 µg/ml | $322.00 | |||
NOS2/iNOS Antibody (C-11): m-IgG Fc BP-HRP Bundle | sc-526492 | 200 µg Ab; 10 µg BP | $361.00 | |||
NOS2/iNOS Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-531865 | 200 µg Ab; 20 µg BP | $361.00 | |||
NOS2/iNOS Antibody (C-11) AC | sc-7271 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NOS2/iNOS Antibody (C-11) HRP | sc-7271 HRP | 200 µg/ml | $322.00 | |||
NOS2/iNOS Antibody (C-11) FITC | sc-7271 FITC | 200 µg/ml | $336.00 | |||
NOS2/iNOS Antibody (C-11) PE | sc-7271 PE | 200 µg/ml | $349.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 488 | sc-7271 AF488 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 546 | sc-7271 AF546 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 594 | sc-7271 AF594 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 647 | sc-7271 AF647 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 680 | sc-7271 AF680 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 790 | sc-7271 AF790 | 200 µg/ml | $364.00 | |||
NOS2/iNOS Antibody (C-11) TRITC | sc-7271 TRITC | 200 µg/ml | $326.00 | |||
NOS2/iNOS Antibody (C-11) Alexa Fluor® 405 | sc-7271 AF405 | 200 µg/ml | $364.00 | |||
NOS2/iNOS (C-11) Neutralizing Peptide | sc-7271 P | 100 µg/0.5 ml | $69.00 |