pan NOS Antibody (NOS-3F7-B11 B5): sc-58399

pan NOS Antibody (NOS-3F7-B11 B5) is a mouse monoclonal IgM antibody engineered to detect all isoforms of Nitric Oxide Synthase (NOS), including neuronal NOS (nNOS or NOS1), inducible NOS (iNOS or NOS2), and endothelial NOS (eNOS or NOS3). pan NOS monoclonal antibody (NOS-3F7-B11 B5) is raised against purified bovine NOS and targets a conserved epitope, allowing broad species reactivity across mouse, rat, bovine, and canine samples. NOS enzymes are essential for the synthesis of nitric oxide (NO), a critical signaling molecule involved in various physiological processes such as neurotransmission, vascular regulation, and immune responses. The distinct cellular localization of each NOS isoform is crucial for their specific functions: nNOS is predominantly located in neurons, where it regulates neurotransmitter release; eNOS is found in endothelial cells, where it controls vascular tone and blood flow; and iNOS is expressed in immune cells, playing a key role in inflammatory responses. anti-pan NOS antibody (NOS-3F7-B11 B5) enables precise detection and localization of NOS isoforms in applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). This comprehensive detection capability makes pan NOS monoclonal antibody (NOS-3F7-B11 B5) an invaluable tool for researchers studying NO signaling pathways, vascular biology, neurobiology, and immune mechanisms. pan NOS (NOS-3F7-B11 B5) antibody provides reliable and detailed insights when investigating the distribution and regulation of NOS enzymes or exploring their roles in various disease states.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-pan NOS Antibody (NOS-3F7-B11 B5) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-pan NOS Antibody (NOS-3F7-B11 B5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

pan NOS Antibody (NOS-3F7-B11 B5) Specifications

Alternate Product Name: pan NOS

Product Clone Name: NOS-3F7-B11 B5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM

Amino Acids:

Epitope Target: NOS

Epitope Species: bovine

Product Reactivity/Detection: brain Nitric Oxide Synthase (bNOS), inducible NOS (iNOS) and epithelial NOS (eNOS)

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: bovine and canine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgM in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for pan NOS Antibody (NOS-3F7-B11 B5): N/A

The preferred NOS2/iNOS antibody is NOS2/iNOS Antibody (C-11): sc-7271.