Nodal Antibody (A-9): sc-377508
- Nodal Antibody (A-9) is a mouse monoclonal IgG1 (lambda light chain) provided at 200 µg/ml
- specific for an epitope mapping between amino acids 291-329 near the C-terminus of Nodal of mouse origin
- recommended for detection of precursor and mature Nodal of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Nodal Antibody (A-9) for WB applications. These reagents are now offered in bundles with Nodal Antibody (A-9) (see ordering information below).
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Nodal Antibody (A-9) is a mouse monoclonal IgG1 antibody that detects Nodal in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nodal is a crucial member of the transforming growth factor β (TGFβ) superfamily, playing a significant role in embryonic development and the maintenance of adult tissue homeostasis. anti-Nodal antibody (A-9) is primarily located in the embryonic cells during the early stages of development, particularly in the primitive streak, where Nodal is essential for mesoderm formation. Nodal (A-9) antibody detects this protein at a critical juncture, indicating Nodal′s vital function in orchestrating the differentiation of ectodermal cells into mesoderm, which is foundational for the development of various tissues and organs. Furthermore, Nodal is implicated in the directional processes of heart looping and embryonic turning, highlighting Nodal′s importance in establishing proper embryonic morphology. Nodal monoclonal antibody (A-9) is an invaluable tool for researchers studying developmental biology and the intricate signaling pathways that govern early embryogenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nodal Antibody (A-9) | sc-377508 | 200 µg/ml | $322.00 | |||
Nodal Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-540731 | 200 µg Ab; 10 µg BP | $361.00 | |||
Nodal Antibody (A-9): m-IgG1 BP-HRP Bundle | sc-542331 | 200 µg Ab; 20 µg BP | $361.00 | |||
Nodal (A-9) Neutralizing Peptide | sc-377508 P | 100 µg/0.5 ml | $69.00 |