NMT2 Antibody (30): sc-136005

NMT2 Antibody (30) is a mouse monoclonal IgG1 kappa light chain antibody that detects the NMT2 protein of human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-NMT2 antibody (30) is available as a non-conjugated monoclonal isotype antibody. NMT2 (30) antibody plays a vital role in studying N-terminal myristoylation, a cotranslational lipid modification essential for proper targeting and function of numerous signaling proteins. This modification influences protein localization, stability, and interactions, thereby impacting various cellular signaling pathways. N-myristoyltransferases, including NMT1 and NMT2, are cytoplasmic enzymes that belong to the NMT family and catalyze the addition of a myristoyl group to the N-terminal glycine residue of eukaryotic, fungal, and viral proteins. These proteins are predominantly found in tissues such as the heart, gut, kidney, liver, and placenta, highlighting their significance in various physiological processes. NMT2′s ability to modify proteins through myristoylation underscores its importance in cellular signaling and potential implications in disease mechanisms, making NMT2 (30) monoclonal antibody a valuable tool for researchers studying these pathways.

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NMT2 Antibody (30) References:

1. Altered expression and localization of N-myristoyltransferase in experimentally induced rat model of ischemia-reperfusion.  |  Rajala, RV., et al. 2002. J Cell Biochem. 86: 509-19. PMID: 12210757
2. Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29.  |  Selvakumar, P., et al. 2004. Biochem Biophys Res Commun. 322: 1012-7. PMID: 15336565
3. Potential role of N-myristoyltransferase in pathogenic conditions.  |  Sharma, RK. 2004. Can J Physiol Pharmacol. 82: 849-59. PMID: 15573145
4. Functional analysis of TbARL1, an N-myristoylated Golgi protein essential for viability in bloodstream trypanosomes.  |  Price, HP., et al. 2005. J Cell Sci. 118: 831-41. PMID: 15687105
5. N-myristoyltransferase 1 is essential in early mouse development.  |  Yang, SH., et al. 2005. J Biol Chem. 280: 18990-5. PMID: 15753093
6. Expression of N-myristoyltransferase in human brain tumors.  |  Lu, Y., et al. 2005. Neurochem Res. 30: 9-13. PMID: 15756927
7. Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism.  |  Pasha, MK., et al. 2005. Int J Mol Med. 15: 987-91. PMID: 15870904
8. Characterization of a polyhistidine-tagged form of human myristoyl-CoA: protein N-myristoyltransferase produced in Escherichia coli.  |  McIlhinney, RA., et al. 1994. Eur J Biochem. 222: 137-46. PMID: 8200338
9. Crystal structure of the anti-fungal target N-myristoyl transferase.  |  Weston, SA., et al. 1998. Nat Struct Biol. 5: 213-21. PMID: 9501915

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NMT2 Antibody (30) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-NMT2 Antibody (30) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NMT2 Antibody (30) Specifications

Alternate Product Name: NMT2

Product Clone Name: 30

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 10-119

Epitope Target: NMT2

Epitope Species: human

Product Reactivity/Detection: NMT2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for NMT2 Antibody (30): N/A