nm23-H7 Antibody (B-9): sc-166677
- nm23-H7 Antibody (B-9) is a mouse monoclonal IgG1 κ nm23-H7 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 100-376 mapping at the C-terminus of nm23-H7 of human origin
- nm23-H7 Antibody (B-9) is recommended for detection of nm23-H7 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-nm23-H7 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for nm23-H7 Antibody (B-9) for WB applications. These reagents are now offered in bundles with nm23-H7 Antibody (B-9) (see ordering information below).
nm23-H7 Antibody (B-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects nm23-H7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). nm23-H7 (B-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid protein that features one DM10 domain and belongs to the nucleoside diphosphate kinase (NDK) family. nm23-H7 plays a crucial role in cellular metabolism by catalyzing the ATP-dependent synthesis of nucleoside triphosphates, which are vital for energy transfer and signaling within cells. Proper functioning of nm23-H7 is essential for maintaining cellular energy levels and supporting various metabolic pathways, making nm23-H7 a significant player in processes such as cell proliferation and differentiation. nm23-H7 is encoded on human chromosome 1, a region rich in genes and associated with numerous diseases, including various cancers and genetic disorders. Aberrations in chromosome 1 can lead to significant health implications, underscoring the importance of studying nm23-H7 in both normal physiology and disease contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
nm23-H7 Antibody (B-9) References:
- The human Nm23/nucleoside diphosphate kinases. | Lacombe, ML., et al. 2000. J Bioenerg Biomembr. 32: 247-58. PMID: 11768308
- Nm23/nucleoside diphosphate kinase in human cancers. | Hartsough, MT. and Steeg, PS. 2000. J Bioenerg Biomembr. 32: 301-8. PMID: 11768314
- Regulation of cellular functions by nucleoside diphosphate kinases in mammals. | Kimura, N., et al. 2000. J Bioenerg Biomembr. 32: 309-15. PMID: 11768315
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Regulation of cardiac cAMP synthesis and contractility by nucleoside diphosphate kinase B/G protein beta gamma dimer complexes. | Hippe, HJ., et al. 2007. Circ Res. 100: 1191-9. PMID: 17363702
- Clinical significance of nm23 gene expression in gastric cancer. | Mönig, SP., et al. 2007. Anticancer Res. 27: 3029-33. PMID: 17695492
- The primitive growth factor NME7AB induces mitochondrially active naïve-like pluripotent stem cells. | O'Reilly, C., et al. 2019. Biochem Biophys Rep. 20: 100656. PMID: 31467990
- Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma. | Landwehr, LS., et al. 2020. J Immunother Cancer. 8: PMID: 32474412
- Heterozygous Nme7 Mutation Affects Glucose Tolerance in Male Rats. | Šedová, L., et al. 2021. Genes (Basel). 12: PMID: 34356103
- The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma. | Ren, X., et al. 2022. Cancer Res. 82: 60-74. PMID: 34764205
- NME7 maintains primary cilium assembly, ciliary microtubule stability, and Hedgehog signaling. | Ji, M., et al. 2025. Life Sci Alliance. 8: PMID: 39824631
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
nm23-H7 Antibody (B-9) | sc-166677 | 200 µg/ml | $316.00 | |||
nm23-H7 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-529028 | 200 µg Ab; 10 µg BP | $354.00 | |||
nm23-H7 Antibody (B-9): m-IgGκ BP-HRP Bundle | sc-521706 | 200 µg Ab, 40 µg BP | $354.00 | |||
nm23-H7 Antibody (B-9): m-IgG1 BP-HRP Bundle | sc-543277 | 200 µg Ab; 20 µg BP | $354.00 | |||
nm23-H7 Antibody (B-9) AC | sc-166677 AC | 500 µg/ml, 25% agarose | $416.00 | |||
nm23-H7 Antibody (B-9) HRP | sc-166677 HRP | 200 µg/ml | $316.00 | |||
nm23-H7 Antibody (B-9) FITC | sc-166677 FITC | 200 µg/ml | $330.00 | |||
nm23-H7 Antibody (B-9) PE | sc-166677 PE | 200 µg/ml | $343.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 488 | sc-166677 AF488 | 200 µg/ml | $357.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 546 | sc-166677 AF546 | 200 µg/ml | $357.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 594 | sc-166677 AF594 | 200 µg/ml | $357.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 647 | sc-166677 AF647 | 200 µg/ml | $357.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 680 | sc-166677 AF680 | 200 µg/ml | $357.00 | |||
nm23-H7 Antibody (B-9) Alexa Fluor® 790 | sc-166677 AF790 | 200 µg/ml | $357.00 |