NKp44 Antibody (3.43): sc-53598
- NKp44 Antibody (3.43) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against NKp44 of human origin
- recommended for detection of NKp44 of human origin by FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NKp44 Antibody (3.43). These reagents are now offered in bundles with NKp44 Antibody (3.43) (see ordering information below).
QUICK LINKS
NKp44 Antibody (3.43) is a mouse monoclonal IgG1 antibody that detects NKp44 in human samples through flow cytometry (FCM). NKp44 is a natural cytotoxicity receptor predominantly expressed on interleukin-2-activated human natural killer (NK) cells, playing a crucial role in the immune response against tumor and virally infected cells. NKp44 consists of one immunoglobulin-like extracellular domain, a transmembrane segment, and a cytoplasmic domain, which together facilitate interaction with various ligands and signaling pathways. This structural configuration enhances the cytotoxic capabilities of NK cells, particularly in tumor cell lysis. Prolactin up-regulates and cortisol down-regulates NKp44 surface expression at the transcriptional level, indicating a complex regulatory mechanism that influences immune responses in different physiological states. NKp44 interacts with a cellular ligand, NKp44L, which is expressed during HIV-1 infection and correlates with the progression of CD4+ T cell depletion and increased viral load, highlighting its potential as a therapeutic target in HIV-1 vaccine development. Anti-NKp44 antibody (3.43) serves as an invaluable tool for researchers investigating NK cell activity dynamics and their implications in cancer immunotherapy and viral infections.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NKp44 Antibody (3.43) | sc-53598 | 200 µg/ml | $322.00 | |||
NKp44 Antibody (3.43): m-IgG Fc BP-HRP Bundle | sc-536993 | 200 µg Ab; 10 µg BP | $361.00 | |||
NKp44 Antibody (3.43): m-IgGκ BP-HRP Bundle | sc-534173 | 200 µg Ab; 40 µg BP | $361.00 | |||
NKp44 Antibody (3.43): m-IgG1 BP-HRP Bundle | sc-544945 | 200 µg Ab; 20 µg BP | $361.00 | |||
NKp44 Antibody (3.43) FITC | sc-53598 FITC | 200 µg/ml | $336.00 | |||
NKp44 Antibody (3.43) PE | sc-53598 PE | 200 µg/ml | $349.00 |