NKp44 Antibody (2.29): sc-53597
- NKp44 Antibody (2.29) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against NKp44 of human origin
- recommended for detection of NKp44 of human origin by FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NKp44 Antibody (2.29). These reagents are now offered in bundles with NKp44 Antibody (2.29) (see ordering information below).
QUICK LINKS
NKp44 Antibody (2.29) is a mouse monoclonal IgG1 antibody that detects NKp44 in human samples through flow cytometry (FCM). NKp44 is a natural cytotoxicity receptor predominantly expressed on interleukin-2-activated human natural killer (NK) cells, playing a crucial role in the immune response against tumor and virally infected cells. NKp44 consists of one immunoglobulin-like extracellular domain, a transmembrane segment, and a cytoplasmic domain, which together facilitate interaction with various ligands and signaling pathways. NKp44′s ability to mediate cytotoxicity is influenced by expression levels, which are regulated by hormones such as prolactin and cortisol at the transcriptional level. NKp44 interacts with a cellular ligand known as NKp44L, which is expressed during HIV-1 infection and has been correlated with the progression of CD4+ T cell depletion and increased viral load. This highlights NKp44′s potential as a therapeutic target in the development of vaccines for HIV-1, making anti-NKp44 antibody (2.29) an essential tool for researchers investigating NK cell function and its implications in immunotherapy.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NKp44 Antibody (2.29) | sc-53597 | 200 µg/ml | $316.00 | |||
NKp44 Antibody (2.29): m-IgG Fc BP-HRP Bundle | sc-536992 | 200 µg Ab; 10 µg BP | $354.00 | |||
NKp44 Antibody (2.29): m-IgGκ BP-HRP Bundle | sc-534172 | 200 µg Ab; 40 µg BP | $354.00 | |||
NKp44 Antibody (2.29): m-IgG1 BP-HRP Bundle | sc-544944 | 200 µg Ab; 20 µg BP | $354.00 | |||
NKp44 Antibody (2.29) FITC | sc-53597 FITC | 200 µg/ml | $330.00 | |||
NKp44 Antibody (2.29) PE | sc-53597 PE | 200 µg/ml | $343.00 |