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NKHC2 Antibody (A-2): sc-390951

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Datasheets
  • NKHC2 Antibody (A-2) is a mouse monoclonal IgG1 κ NKHC2 antibody provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 409-432 within an internal region of NKHC2 of human origin
  • NKHC2 Antibody (A-2) is recommended for detection of NKHC2 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-NKHC2 Antibody (A-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NKHC2 Antibody (A-2) for WB applications. These reagents are now offered in bundles with NKHC2 Antibody (A-2) (see ordering information below).
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    NKHC2 Antibody (A-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects NKHC2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NKHC2 (A-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The neuronal kinesin heavy chain 2 (NKHC2) is a 1,032 amino acid protein belonging to the kinesin superfamily, which is crucial for intracellular transport processes. NKHC2 is predominantly expressed in the central nervous system, particularly in specific subsets of neurons, highlighting NKHC2′s importance in neuronal function and health. NKHC2 features a distinctive C-terminal region of 69 amino acids that is essential for interaction with dystrobrevin, an adaptor and scaffolding protein. This interaction may facilitate the transport and localization of components of the dystrophin-associated protein complex to specific cellular sites, thereby playing a vital role in maintaining the structural integrity and functionality of neurons. NKHC2 is implicated in the microtubule-dependent slow axonal transport of neurofilament proteins, which is critical during the maturation of neuronal cells, underscoring NKHC2′s importance in neurodevelopment and potential implications in neurodegenerative diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    NKHC2 Antibody (A-2)

    sc-390951
    200 µg/ml
    $322.00

    NKHC2 Antibody (A-2): m-IgG Fc BP-HRP Bundle

    sc-527655
    200 µg Ab; 10 µg BP
    $361.00

    NKHC2 Antibody (A-2): m-IgG1 BP-HRP Bundle

    sc-533028
    200 µg Ab; 20 µg BP
    $361.00

    NKHC2 Antibody (A-2) AC

    sc-390951 AC
    500 µg/ml, 25% agarose
    $424.00

    NKHC2 Antibody (A-2) HRP

    sc-390951 HRP
    200 µg/ml
    $322.00

    NKHC2 Antibody (A-2) FITC

    sc-390951 FITC
    200 µg/ml
    $336.00

    NKHC2 Antibody (A-2) PE

    sc-390951 PE
    200 µg/ml
    $349.00

    NKHC2 Antibody (A-2) Alexa Fluor® 488

    sc-390951 AF488
    200 µg/ml
    $364.00

    NKHC2 Antibody (A-2) Alexa Fluor® 546

    sc-390951 AF546
    200 µg/ml
    $364.00

    NKHC2 Antibody (A-2) Alexa Fluor® 594

    sc-390951 AF594
    200 µg/ml
    $364.00

    NKHC2 Antibody (A-2) Alexa Fluor® 647

    sc-390951 AF647
    200 µg/ml
    $364.00

    NKHC2 Antibody (A-2) Alexa Fluor® 680

    sc-390951 AF680
    200 µg/ml
    $364.00

    NKHC2 Antibody (A-2) Alexa Fluor® 790

    sc-390951 AF790
    200 µg/ml
    $364.00

    NKHC2 (A-2) Neutralizing Peptide

    sc-390951 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-390951 P appropriate for?

    Asked by: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_4, d_23, h_7CST
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    Rated 4 out of 5 by from Good for IFThis NKHC2 Antibody (A-2), sc-390951, shows strong specific signal in IF staining in primary rat motor neuron.
    Date published: 2018-02-20
    Rated 5 out of 5 by from Produced positive Western blot data of NKHC2Produced positive Western blot data of NKHC2 expression in IMR-32 whole cell lysate and human hippocampus tissue extract . -SCBT QC
    Date published: 2013-10-26
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    NKHC2 Antibody (A-2) is rated 4.5 out of 5 by 2.
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