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NKG2-D Antibody (C7) is a hamster monoclonal IgG antibody that detects NKG2-D protein of mouse origin by flow cytometry (FCM). NKG2-D plays a crucial role in the immune response, particularly in the activation of natural killer (NK) cells and certain T cell populations, serving as a receptor for the stress-inducible protein MICA, which is often overexpressed in various epithelial tumors. The interaction between NKG2-D and MICA is vital for the immune system′s ability to recognize and eliminate transformed or infected cells, thereby contributing to tumor surveillance and overall maintenance of cellular homeostasis. NKG2-D is expressed not only on NK cells but also on γδ T cells and CD8+ αβ T cells, highlighting NKG2-D′s importance in both innate and adaptive immunity. Anti-NKG2-D antibody (C7) serves as an essential tool for researchers studying immune regulation and tumor biology, particularly given NKG2-D′s potential as a therapeutic target in cancer immunotherapy.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NKG2-D Antibody (C7) | sc-23890 | 200 µg/ml | $322.00 | |||
NKG2-D Antibody (C7) L | sc-23890 L | 200 µg/0.1 ml | $322.00 |