Nix Antibody (D-1): sc-166114

Nix Antibody (D-1) is a mouse monoclonal IgG1 kappa antibody targeting the Nix protein, also known as Bnip3L. Nix monoclonal antibody (D-1) is raised against amino acids 1-219, encompassing the full-length human Nix protein, ensuring robust recognition and binding. Nix is predominantly localized to the mitochondria, a critical location that underscores its role in the regulation of apoptosis and mitochondrial quality control. By residing in the mitochondria, Nix interacts with members of the Bcl-2 family, facilitating the initiation of apoptotic signaling pathways essential for cellular homeostasis and the removal of damaged cells. Anti-Nix antibody (D-1) exhibits broad species reactivity, effectively recognizing Nix proteins from mouse, rat, and human origins across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). This versatility makes Nix monoclonal antibody (D-1) an invaluable tool for researchers studying apoptosis, mitochondrial dynamics, and related signaling mechanisms in different model organisms. Additionally, Nix (D-1) antibody′s ability to detect Nix in multiple assay formats enhances its utility in both basic research and clinical settings. By enabling precise detection and analysis of Nix, anti-Nix antibody (D-1) supports advancements in understanding the molecular underpinnings of cell death and its implications in diseases such as cancer and neurodegeneration.

The preferred BNIP-3 antibody is BNIP-3 Antibody (ANa40): sc-56167.