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Nitrotyrosine Antibody (HM.11) is a mouse monoclonal IgG2b light chain antibody that detects nitrotyrosine in non-species reactive samples by western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Anti-nitrotyrosine antibody (HM.11) recognizes a critical biomarker for inflammation and nitric oxide (NO) production, formed when nitric oxide interacts with tyrosine residues in proteins, leading to the formation of peroxynitrite. This post-translational modification indicates oxidative stress and cellular damage, which are pivotal in various pathological conditions. Elevated levels of nitrotyrosine have been associated with numerous inflammatory diseases, including septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques, and chronic renal failure, making nitrotyrosine monoclonal antibody (HM.11) an essential tool for researchers investigating the role of nitric oxide in these conditions. Anti-nitrotyrosine antibody (HM.11) enables scientists to gain insights into the mechanisms of NO-dependent damage and the broader implications of nitrotyrosine in disease progression and therapeutic interventions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nitrotyrosine Antibody (HM.11) | sc-32731 | 100 µg/ml | $316.00 |