Nitrotyrosine Antibody (2A12): sc-65384
- Nitrotyrosine Antibody (2A12) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against 3-Nitrotyrosine
- recommended for detection of nitrosylated tyrosine containing proteins by WB and IP
- See Nitrotyrosine (39B6): sc-32757 for Nitrotyrosine antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nitrotyrosine Antibody (2A12). This work is in progress.
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SEE ALSO...
Nitrotyrosine Antibody (2A12) is a mouse monoclonal IgG1 antibody that detects nitrotyrosine in non-species reactive samples by western blotting (WB) and immunoprecipitation (IP). Nitrotyrosine is a critical biomarker for inflammation and nitric oxide (NO) production, formed when NO interacts with tyrosine residues in proteins, leading to the formation of peroxynitrite. This post-translational modification can indicate oxidative stress and cellular damage, which are pivotal in various pathological conditions. Elevated levels of nitrotyrosine have been associated with numerous inflammatory diseases, including septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques, and chronic renal failure, making anti-nitrotyrosine antibody (2A12) an essential tool for researchers investigating the role of nitric oxide in these conditions. By using nitrotyrosine monoclonal antibody (2A12), scientists can gain insights into the mechanisms of NO-dependent damage and the broader implications of nitrotyrosine in disease progression and therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nitrotyrosine Antibody (2A12) | sc-65384 | 100 µg/ml | $316.00 |