

NGFR p75 Antibody (MC-192) is a mouse monoclonal IgG1 antibody that detects NGFR p75 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). NGFR p75, also known as the p75 neurotrophin receptor, plays a crucial role in the nervous system by modulating the effects of neurotrophic factors, including nerve growth factor (NGF). NGFR p75 is primarily located on the surface of neurons and is essential for neuronal survival, differentiation, and apoptosis. The interaction between NGFR p75 and neurotrophic factors is characterized by low-affinity binding, which allows for the fine-tuning of neuronal responses to these growth factors. NGFR p75 enhances the signaling of the high-affinity Trk receptors, such as Trk A, by accelerating their activation and facilitating the recruitment of downstream signaling molecules. This cooperative interaction is vital for the proper functioning of neuronal circuits and has implications in neurodegenerative diseases and injury responses, making NGFR p75 a key player in neurobiology. Anti-NGFR p75 antibody (MC-192) is an invaluable tool for researchers studying these complex signaling pathways and their effects on neuronal health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NGFR p75 Antibody (MC-192) | sc-53631 | 200 µg/ml | $322.00 | |||
NGFR p75 Antibody (MC-192): m-IgG Fc BP-HRP Bundle | sc-536995 | 200 µg Ab; 10 µg BP | $361.00 | |||
NGFR p75 Antibody (MC-192): m-IgGκ BP-HRP Bundle | sc-534175 | 200 µg Ab; 40 µg BP | $361.00 | |||
NGFR p75 Antibody (MC-192): m-IgG1 BP-HRP Bundle | sc-544946 | 200 µg Ab; 20 µg BP | $361.00 | |||
NGFR p75 Antibody (MC-192) FITC | sc-53631 FITC | 200 µg/ml | $336.00 | |||
NGFR p75 Antibody (MC-192) PE | sc-53631 PE | 200 µg/ml | $349.00 | |||
NGFR p75 Antibody (MC-192) Alexa Fluor® 647 | sc-53631 AF647 | 200 µg/ml | $364.00 |