

NGF Antibody (NGF30) is a rat monoclonal IgG1 antibody raised against nerve growth factor (NGF) of mouse origin, capable of detecting native and denatured NGF from mouse and rat by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). NGF, also known as beta-nerve growth factor, is a critical neurotrophin involved in the regulation of neuronal survival, development, and function. NGF promotes the survival and differentiation of sympathetic and sensory neurons during development and plays a key role in neuroplasticity and repair processes within the adult nervous system. NGF exerts its effects primarily through binding to the high-affinity receptor TrkA (tropomyosin receptor kinase A) but can also interact with the low-affinity receptor p75NTR, influencing a variety of intracellular signaling pathways. Dysregulation of NGF expression or signaling has been implicated in neurodegenerative diseases such as Alzheimer′s disease and peripheral neuropathies, making NGF a significant target for research. Anti-NGF antibody (NGF30) is an essential tool for scientists investigating NGF′s role in neuronal survival, growth, and potential therapeutic applications. NGF monoclonal antibody (NGF30) aids in advancing our understanding of neurotrophin-mediated signaling pathways and their implications in neurological disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NGF Antibody (NGF30) | sc-32300 | 200 µg/ml | $322.00 |