NFκB p50 Antibody (D-6): sc-166588

NFκB p50 Antibody (D-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects NFκB p50 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-NFκB p50 antibody (D-6) is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatility for different experimental needs. NFκB p50 plays a crucial role in the regulation of immune response and inflammation, functioning as a transcription factor that controls the expression of genes involved in these processes. NFκB p50′s ability to translocate from the cytoplasm to the nucleus upon activation by mitogens or growth factors is vital for initiating the transcription of target genes that mediate cellular responses to stress and infection. NFκB p50 is derived from the processing of precursor p105, which not only produces NFκB p50 but also contains regulatory domains that influence NFκB p50′s activity. Understanding NFκB p50 dynamics and interactions is essential for elucidating NFκB p50′s role in various diseases, including cancer and autoimmune disorders, making NFκB p50 monoclonal antibody (D-6) an invaluable tool for researchers studying these critical biological pathways.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NFκB p50 Antibody (D-6) has 41 citations in a variety of scientific publications.

Primary antibodies like Anti-NFκB p50 Antibody (D-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NFκB p50 Antibody (D-6) Specifications

Alternate Product Name: NFKB1

Product Clone Name: D-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 338-357

Epitope Target: NFκB p50

Epitope Species: human

Product Reactivity/Detection: NFκB p50 and p105

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine, bovine, porcine and avian

Additional Non-Mammalian Reactivity: avian

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 41 citations in various scientific publications

Available Conjugates/Forms for NFκB p50 Antibody (D-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent

The preferred NFκB p50 antibody is NFκB p50 Antibody (E-10): sc-8414.