NEIL1 Antibody (D-4): sc-365302
- NEIL1 Antibody (D-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 23-51 near the N-terminus of NEIL1 of human origin
- recommended for detection of NEIL1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365302 X, 200 µg/0.1 ml)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NEIL1 Antibody (D-4). This work is in progress.
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NEIL1 Antibody (D-4) is a mouse monoclonal IgG1 antibody that detects NEIL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NEIL1, also known as Endonuclease VIII-like 1, plays a crucial role in the repair of oxidatively damaged DNA, which is vital for maintaining genomic stability and preventing mutations that could lead to diseases such as cancer. NEIL1 is predominantly located in the nucleus, where NEIL1 functions as a DNA glycosylase, recognizing and excising damaged bases to create abasic sites that can be further processed by other repair mechanisms. Anti-NEIL1 antibody (D-4) efficiently detects DNA damage repair activity during the S-phase of the cell cycle, where DNA replication occurs, and the risk of oxidative damage is heightened. NEIL1 is ubiquitously expressed, with expression levels increasing during DNA synthesis, highlighting NEIL1′s essential role in cellular responses to DNA damage. NEIL1 (D-4) antibody serves as an invaluable tool for researchers studying DNA repair mechanisms and the implications of oxidative stress in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NEIL1 Antibody (D-4) | sc-365302 | 200 µg/ml | $316.00 | |||
NEIL1 (D-4) Neutralizing Peptide | sc-365302 P | 100 µg/0.5 ml | $68.00 | |||
NEIL1 Antibody (D-4) X | sc-365302 X | 200 µg/0.1 ml | $316.00 |