NE-dlg Antibody (D-6): sc-376144
- NE-dlg Antibody (D-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 14-41 at the N-terminus of NE-dlg of human origin
- recommended for detection of NE-dlg of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including porcine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NE-dlg Antibody (D-6) for WB and IHC(P) applications. These reagents are now offered in bundles with NE-dlg Antibody (D-6) (see ordering information below).
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SEE ALSO...
NE-dlg Antibody (D-6) is a mouse monoclonal IgG1 antibody that detects NE-dlg in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). NE-dlg, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in synaptic signaling and cellular architecture by localizing at the membrane-cytoskeleton interface. This localization facilitates the assembly of protein complexes essential for maintaining synaptic integrity and mediating intracellular signaling pathways. The structural features of NE-dlg, including distinct PDZ, SH3, and guanylate kinase domains, enable interactions with various signaling molecules and cytoskeletal components, influencing processes such as cell adhesion, growth regulation, and synaptic plasticity. NE-dlg has been shown to interact with the tumor suppressor protein APC, suggesting involvement in growth regulation and potential implications in cancer biology. With broad species reactivity and versatility in multiple applications, anti-NE-dlg antibody (D-6) serves as an invaluable tool for researchers studying synaptic function and related signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NE-dlg Antibody (D-6) | sc-376144 | 200 µg/ml | $322.00 | |||
NE-dlg Antibody (D-6): m-IgG Fc BP-HRP Bundle | sc-540520 | 200 µg Ab; 10 µg BP | $361.00 | |||
NE-dlg Antibody (D-6): m-IgG1 BP-HRP Bundle | sc-542178 | 200 µg Ab; 20 µg BP | $361.00 | |||
NE-dlg (D-6) Neutralizing Peptide | sc-376144 P | 100 µg/0.5 ml | $69.00 |