Date published: 2025-10-15

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NE-dlg Activators

NE-dlg activators refer to a selection of chemical compounds that have been identified or designed to augment the functionality or expression of the NE-dlg protein. NE-dlg, part of the DLG (Discs large) family of proteins, plays critical roles in various cellular events, spanning from cell polarity and proliferation to synaptic signaling. Its significance is emphasized by its interactions with numerous cellular partners and its involvement in diverse signaling cascades. Given the multifaceted nature of NE-dlg in cellular physiology, the precise modulation of its activity using chemical activators becomes an area of substantial interest.

Chemicals that fall under the classification of NE-dlg activators typically operate through distinct mechanisms to amplify the activity or expression of NE-dlg. Some activators might enhance the protein's direct interactions with its cellular partners, reinforcing its role in signal transduction pathways. Others might act by preserving the protein's stability within the cellular milieu, ensuring its enduring presence and consequent functionality. Additionally, certain compounds might stimulate the transcription or translation of the NE-dlg gene, leading to a surge in protein levels within the cell. On a molecular spectrum, these activators might achieve their function either by directly binding to NE-dlg, altering its structure to a more active configuration, or by modulating cellular pathways that supervise NE-dlg's expression or activity. A comprehensive grasp of NE-dlg activators not only deepens our understanding of cellular signaling dynamics but also paves the way for more informed explorations in the realm of cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

As a histone deacetylase (HDAC) inhibitor, it can promote a more relaxed chromatin state. This can enhance the transcription of genes, potentially including NE-DLG if its expression is regulated by histone acetylation.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

By increasing cellular cAMP levels, Forskolin activates the cAMP-dependent protein kinase A (PKA) pathway. If NE-DLG is part of a signaling cascade modulated by PKA, its activity or expression might be influenced.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

As an activator of protein kinase C (PKC), PMA might affect proteins downstream of PKC signaling, potentially impacting NE-DLG expression or activity.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

As a glucocorticoid, it modulates a plethora of cellular responses, and might influence NE-DLG expression in a context-dependent manner.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A polyphenol from green tea, known to modulate multiple cellular pathways, potentially influencing NE-DLG expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

An inducer of phase II detoxification enzymes, it might influence cellular stress responses, potentially impacting NE-DLG expression.