NDUFS8 Antibody (D-5): sc-515537
- NDUFS8 Antibody (D-5) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 163-187 within an internal region of NDUFS8 of human origin
- recommended for detection of NDUFS8 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for NDUFS8 Antibody (D-5) for WB applications. This reagent is now offered in a bundle with NDUFS8 Antibody (D-5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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NDUFS8 Antibody (D-5) is a mouse monoclonal IgM antibody that detects NDUFS8 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NDUFS8, also known as NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, plays a crucial role as a subunit of mitochondrial complex I, which is essential for the electron transport chain in oxidative phosphorylation. This complex is responsible for the oxidation of NADH produced during the Krebs cycle, facilitating the reduction of ubiquinone to ubiquinol and enabling the transfer of electrons through the chain, ultimately leading to the reduction of oxygen to water. NDUFS8 consists of 210 amino acids and is vital for the overall stability and activity of mitochondrial complex I. Defects in the NDUFS8 gene can lead to severe clinical conditions, such as Leigh syndrome, characterized by necrotic lesions in the brain, highlighting NDUFS8′s significance in maintaining mitochondrial function and overall cellular health. Anti-NDUFS8 antibody (D-5) is an invaluable tool for researchers studying mitochondrial dysfunction and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDUFS8 Antibody (D-5) | sc-515537 | 200 µg/ml | $322.00 | |||
NDUFS8 Antibody (D-5): m-IgGκ BP-HRP Bundle | sc-552186 | 200 µg Ab; 40 µg BP | $361.00 | |||
NDUFS8 (D-5) Neutralizing Peptide | sc-515537 P | 100 µg/0.5 ml | $69.00 |