NDUFB11 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects NDUFB11 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). NDUFB11, also known as NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11, ESSS, Np15, Np17.3, or p17.3, is a crucial hydrophobic transmembrane protein that plays a significant role as an accessory subunit of Complex I in the mitochondrial inner membrane. NDUFB11 is essential for the proper functioning of the electron transport chain, facilitating the transfer of electrons from NADH to ubiquinone, ultimately contributing to ATP synthesis through the establishment of an electrochemical proton gradient. The phosphorylation of NDUFB11 by cAMP-dependent protein kinases regulates Complex I activity, thereby influencing cellular energy metabolism. Given NDUFB11′s ubiquitous expression and vital role in mitochondrial function, NDUFB11 serves as a key player in cellular respiration and energy production, making NDUFB11 a valuable target for research in metabolic disorders and mitochondrial dysfunction.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDUFB11 Antibody (F-3) | sc-393074 | 200 µg/ml | $316.00 | |||
NDUFB11 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-538133 | 200 µg Ab; 10 µg BP | $354.00 | |||
NDUFB11 Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-535692 | 200 µg Ab; 40 µg BP | $354.00 | |||
NDUFB11 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-545540 | 200 µg Ab; 20 µg BP | $354.00 |