NDH II Antibody (B-5): sc-137198
- NDH II Antibody (B-5) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of NDH II of human origin
- recommended for detection of nuclear DNA helicase II of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-137198 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NDH II Antibody (B-5) for WB applications. These reagents are now offered in bundles with NDH II Antibody (B-5) (see ordering information below).
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NDH II Antibody (B-5) is a mouse monoclonal IgG1 antibody that detects NDH II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NDH II, also known as RNA helicase A, plays a crucial role in the unwinding of RNA secondary structures, which is essential for various RNA processing events, including splicing and translation. Anti-NDH II antibody (B-5) facilitates the study of RNA-binding protein interactions with target RNA molecules, influencing gene expression and cellular responses. NDH II modulates RNA structure for growth, differentiation, and apoptosis of cells, including human melanoma cells, highlighting its significance in cancer biology and potential therapeutic targets. NDH II (B-5) monoclonal antibody provides a reliable tool for researchers investigating the dynamics of RNA processing and molecular mechanisms underlying gene regulation in various biological contexts.
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NDH II Antibody (B-5) References:
- Pre-mRNA and mRNA binding of human nuclear DNA helicase II (RNA helicase A). | Zhang, S., et al. 1999. J Cell Sci. 112 (Pt 7): 1055-64. PMID: 10198287
- Dual roles of RNA helicase A in CREB-dependent transcription. | Aratani, S., et al. 2001. Mol Cell Biol. 21: 4460-9. PMID: 11416126
- Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity. | Friedemann, J., et al. 2005. J Biol Chem. 280: 31303-13. PMID: 15995249
- RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II. | Tang, W., et al. 2009. Biochem J. 420: 421-8. PMID: 19309309
- RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions. | Bolinger, C., et al. 2010. Nucleic Acids Res. 38: 1686-96. PMID: 20007598
- Molecular characterization of nuclear DNA helicase II (RNA helicase A). | Zhang, S. and Grosse, F. 2010. Methods Mol Biol. 587: 291-302. PMID: 20225158
- Identification of RNA helicase A as a cellular factor that interacts with influenza A virus NS1 protein and its role in the virus life cycle. | Lin, L., et al. 2012. J Virol. 86: 1942-54. PMID: 22171255
- Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism. | Xing, L., et al. 2013. PLoS One. 8: e78596. PMID: 24223160
- Substrate Determinants for Unwinding Activity of the DExH/D-Box Protein RNA Helicase A. | Xie, Q., et al. 2018. Biochemistry. 57: 6662-6668. PMID: 30406989
- A role for RNA helicase A in post-transcriptional regulation of HIV type 1. | Li, J., et al. 1999. Proc Natl Acad Sci U S A. 96: 709-14. PMID: 9892698
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDH II Antibody (B-5) | sc-137198 | 200 µg/ml | $322.00 | |||
NDH II Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-539956 | 200 µg Ab; 10 µg BP | $361.00 | |||
NDH II Antibody (B-5): m-IgG1 BP-HRP Bundle | sc-541812 | 200 µg Ab; 20 µg BP | $361.00 | |||
NDH II Antibody (B-5) X | sc-137198 X | 200 µg/0.1 ml | $322.00 |