Anti-NAPRT Antibody (B-8) is a mouse monoclonal IgG2a κ NAPRT antibody, cited in 2 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 141-162 within an internal region of NAPRT of human origin
Anti-NAPRT Antibody (B-8) is recommended for detection of NAPRT of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-NAPRT Antibody (B-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of NAPRT (B-8): sc-398404.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for NAPRT Antibody (B-8) for WB applications. These reagents are now offered in bundles with NAPRT Antibody (B-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
NAPRT Antibody (B-8) is a high quality monoclonal NAPRT antibody (also designated NAPRT antibody) suitable for the detection of the NAPRT protein of mouse, rat and human origin. NAPRT Antibody (B-8) is available as both the non-conjugated anti-NAPRT antibody form, as well as multiple conjugated forms of anti-NAPRT antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. NAPRT (nicotinate phosphoribosyltransferase), also known as FHA-HIT-interacting protein or nicotinate phosphoribosyltransferase domain-containing protein 1, is a 538 amino acid member of the NAPRTase protein family. Localized to the cytoplasm, NAPRT is involved in the biosynthesis of the cofactor NAD(+). NAPRT catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). This conversion is essential to increase cellular NAD levels, which prevents oxidative stress of the cells. NAPRT is expressed as three isoforms produced by alternative splicing events. The gene that encodes NAPRT maps to human chromosome 8, which makes up nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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