Nanos2 Antibody (A-8): sc-393868
- Nanos2 Antibody (A-8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 38-67 within an internal region of Nanos2 of human origin
- recommended for detection of Nanos2 of human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Nanos2 Antibody (A-8) for WB applications. These reagents are now offered in bundles with Nanos2 Antibody (A-8) (see ordering information below).
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Nanos2 Antibody (A-8) is a mouse monoclonal IgG2b light chain antibody that detects Nanos2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nanos2 is a 138 amino acid protein characterized by a nanos-type zinc finger structure, which consists of two C2HC motifs that bind zinc ions and are crucial for its role in translational regulation. This structural feature enables Nanos2 to interact with specific mRNAs, potentially influencing their translation by binding to the 3′-untranslated region of target transcripts. Expressed predominantly in male germ cells, Nanos2 is vital for the formation of spermatogonia and supports the self-renewal, proliferation, and overall development of proximal germ cells. The gene encoding human Nanos2 is located on chromosome 19, a region that also harbors various immunoglobulin superfamily members, including killer cell and leukocyte immunoglobulin-like receptors, as well as several intercellular adhesion molecules and Fc receptors. anti-Nanos2 antibody (A-8) is an essential tool for researchers studying male germ cell development and the regulatory mechanisms of gene expression in reproductive biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nanos2 Antibody (A-8) | sc-393868 | 200 µg/ml | $322.00 | |||
Nanos2 Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-535913 | 200 µg Ab; 40 µg BP | $361.00 | |||
Nanos2 Antibody (A-8): m-IgG2b BP-HRP Bundle | sc-549487 | 200 µg Ab; 10 µg BP | $361.00 | |||
Nanos2 (A-8) Neutralizing Peptide | sc-393868 P | 100 µg/0.5 ml | $69.00 |