Nanog Antibody (C-4): sc-376915

Nanog Antibody (C-4) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect Nanog protein of mouse origin across various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Nanog antibody (C-4) is raised against amino acids 181-329, mapping to the C-terminus of Nanog protein, ensuring accurate recognition and binding to the targeted epitope. Nanog, also called Nanog homeobox, is a pivotal homeodomain-containing transcription factor that plays a critical role in maintaining pluripotency and self-renewal of embryonic stem cells, preventing their differentiation into specialized cell types. By regulating the expression of key genes involved in maintaining an undifferentiated state, Nanog (C-4) monoclonal antibody enables the study and manipulation of stem cell properties necessary for tissue regeneration and repair. Nanog orchestrates gene expression programs that sustain the pluripotent state, enabling scientists to understand and harness the mechanisms underlying cellular reprogramming and differentiation. Nanog monoclonal antibody (C-4) serves as an indispensable tool for researchers investigating molecular pathways that govern stem cell maintenance and differentiation, facilitating advancements in therapeutic strategies aimed at treating various diseases and injuries. With high affinity and specificity for mouse Nanog protein, anti-Nanog antibody (C-4) supports comprehensive studies into fundamental processes of cellular pluripotency and differentiation, contributing to significant breakthroughs in stem cell biology and innovative biomedical applications.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Nanog Antibody (C-4) has 30 citations in a variety of scientific publications.

Primary antibodies like Anti-Nanog Antibody (C-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Nanog Antibody (C-4) Specifications

Alternate Product Name: Nanog homeobox

Product Clone Name: C-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 181-329

Epitope Target: Nanog

Epitope Species: mouse

Product Reactivity/Detection: Nanog

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 30 citations in various scientific publications

Available Conjugates/Forms for Nanog Antibody (C-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Nanog antibody is Nanog Antibody (5A10): sc-134218.