Nanog Antibody (A-11): sc-374001
- Nanog Antibody (A-11) is a mouse monoclonal IgG1 κ, cited in 20 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 267-301 near the C-terminus of Nanog of mouse origin
- Anti-Nanog Antibody (A-11) is recommended for detection of Nanog of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Nanog Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Nanog Antibody (A-11) for WB applications. These reagents are now offered in bundles with Nanog Antibody (A-11) (see ordering information below).
QUICK LINKS
SEE ALSO...
Nanog Antibody (A-11) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Nanog from mouse, rat, and human origins through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Nanog antibody (A-11) targets a precise epitope mapping between amino acids 267-301 near the C-terminus of mouse Nanog, ensuring accurate recognition and binding. Nanog, also called Nanog homeobox, is a critical homeodomain-containing transcription factor that plays a pivotal role in maintaining pluripotency and self-renewal of embryonic stem cells, thereby preventing differentiation. Structurally, Nanog consists of a conserved homeodomain essential for specific DNA binding, as well as regions that facilitate protein-protein interactions, which are crucial for forming complexes that regulate gene expression networks involved in stem cell maintenance. Nanog undergoes various post-translational modifications, including phosphorylation, acetylation, ubiquitination, and sumoylation. These modifications regulate Nanog′s stability, subcellular localization, and interaction with other regulatory proteins, thereby modulating activity and ensuring precise control over stem cell pluripotency and differentiation processes. Nanog monoclonal antibody (A-11) recognizes Nanog across different species and detects these modified forms, making anti-Nanog antibody (A-11) an invaluable tool for researchers studying stem cell biology, developmental biology, and regenerative medicine. By facilitating accurate detection and analysis of Nanog and post-translationally modified states, Nanog (A-11) antibody supports comprehensive investigations into how Nanog governs cellular fate decisions and maintains undifferentiated states of pluripotent cells, enhancing understanding of stem cell regulation and aiding development of therapeutic strategies for tissue regeneration and repair.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nanog Antibody (A-11) | sc-374001 | 200 µg/ml | $322.00 | |||
Nanog Antibody (A-11): m-IgG Fc BP-HRP Bundle | sc-527428 | 200 µg Ab; 10 µg BP | $361.00 | |||
Nanog Antibody (A-11): m-IgG1 BP-HRP Bundle | sc-532801 | 200 µg Ab; 20 µg BP | $361.00 | |||
Nanog Antibody (A-11) AC | sc-374001 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Nanog Antibody (A-11) HRP | sc-374001 HRP | 200 µg/ml | $322.00 | |||
Nanog Antibody (A-11) FITC | sc-374001 FITC | 200 µg/ml | $336.00 | |||
Nanog Antibody (A-11) PE | sc-374001 PE | 200 µg/ml | $349.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 488 | sc-374001 AF488 | 200 µg/ml | $364.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 546 | sc-374001 AF546 | 200 µg/ml | $364.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 594 | sc-374001 AF594 | 200 µg/ml | $364.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 647 | sc-374001 AF647 | 200 µg/ml | $364.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 680 | sc-374001 AF680 | 200 µg/ml | $364.00 | |||
Nanog Antibody (A-11) Alexa Fluor® 790 | sc-374001 AF790 | 200 µg/ml | $364.00 | |||
Nanog (A-11) Neutralizing Peptide | sc-374001 P | 100 µg/0.5 ml | $69.00 |