NaBC1 Antibody (5): sc-136342
- NaBC1 Antibody (5) is a mouse monoclonal IgG1 κ, cited in 17 publications, provided at 200 µg/ml
- raised against amino acids 365-571 of NaBC1 of human origin
- recommended for detection of NaBC1 of human origin by WB, IP and IF
- m-IgG1 BP-HRP is the preferred secondary detection reagent for NaBC1 Antibody (5) for WB applications. This reagent is now offered in a bundle with NaBC1 Antibody (5) (see ordering information below).
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NaBC1 Antibody (5) is a mouse monoclonal IgG1 antibody that detects NaBC1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). NaBC1, also known as Novel amplified in breast cancer 1, plays a crucial role in breast cancer biology, as NaBC1 is often found amplified in various forms of breast carcinoma. NaBC1 is primarily located in the cytoplasm, where NaBC1 exists as a detergent-stable homodimer, and this localization suggests a potential role in intracellular signaling pathways that may influence tumor progression. NaBC1 interacts with proteins such as DYNLL1 and DYNLL2, which are involved in cellular transport and signaling, further implicating NaBC1 in the complex network of interactions that govern cell behavior in cancer. While breast tumor lines with 20q13.2 gene amplification show elevated levels of NaBC1, this upregulation does not correlate with increased growth rates or anchoring abilities, indicating that NaBC1′s oncogenic properties may operate through mechanisms distinct from those of other oncogenes. Anti-NaBC1 antibody (5) is an essential tool for researchers investigating NaBC1′s role in breast cancer and potential as a therapeutic target.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NaBC1 Antibody (5) | sc-136342 | 200 µg/ml | $322.00 | |||
NaBC1 Antibody (5): m-IgG1 BP-HRP Bundle | sc-542646 | 200 µg Ab; 20 µg BP | $361.00 |