Myosin-2/MYH2 Antibody (6D595): sc-71632

MYH2 Antibody (6D595) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect the MYH2 protein, also known as myosin heavy chain 2, MyHC-IIa, Myosin-2, or MYHSA2, in mouse, rat, human, rabbit, and fish tissues. MYH2 monoclonal antibody (6D595) targets neonatal slow-like MYH2, raised against neonatal skeletal muscle myosin of human origin, and is validated for use in western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. MYH2 is a critical component of the sarcomeric thick filaments in skeletal muscle fibers, playing a key role in muscle contraction by interacting with actin filaments to generate force. MYH2 interacts with several essential proteins, including actin, myosin light chains, tropomyosin, and the troponin complex, forming a complex machinery that regulates muscle contraction and relaxation. These interactions are crucial for coordinating the sliding of filaments necessary for muscle movement, as well as for muscle development, adaptation, and repair. By enabling accurate detection of MYH2, anti-MYH2 antibody (6D595) facilitates detailed analysis of muscle fiber composition and the molecular mechanisms underlying muscle physiology and pathology. MYH2 (6D595) antibody is an indispensable tool for researchers investigating muscle function, muscle adaptation, and muscle-related disorders.

The preferred antibody is Antibody (): sc-32732m.