myoglobin Antibody (8): sc-130332
- myoglobin Antibody (8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant myoglobin of human origin
- recommended for detection of myoglobin of human origin by WB, IP and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for myoglobin Antibody (8) for WB applications. These reagents are now offered in bundles with myoglobin Antibody (8) (see ordering information below).
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Myoglobin Antibody (8) is a mouse monoclonal IgG1 antibody that detects myoglobin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Myoglobin is a crucial cytosolic oxygen-binding protein primarily found in skeletal and cardiac muscle, where myoglobin plays a vital role in the storage and diffusion of oxygen within myocytes. Anti-myoglobin antibody (8) is essential for maintaining mitochondrial respiration during periods of intense and sustained muscle contraction, effectively transporting oxygen from erythrocytes to mitochondria to support aerobic metabolism. The structure of myoglobin, characterized by its globular shape and heme group, allows myoglobin to bind oxygen efficiently, which is critical for muscle function and endurance. Notably, the genomic structure of myoglobin is conserved across various species, featuring a putative polyadenylation signal and a polypyrimidine-rich region, which underscores myoglobin′s evolutionary importance. Human myoglobin is encoded by a single gene and has also been identified in human smooth muscle, further highlighting myoglobin′s significance in different muscle types. Myoglobin monoclonal antibody (8) is an invaluable tool for researchers studying muscle physiology and related disorders.
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myoglobin Antibody (8) References:
- Amyloid fibrils from muscle myoglobin. | Fändrich, M., et al. 2001. Nature. 410: 165-6. PMID: 11242064
- Peroxynitrite isomerization catalyzed by his64 myoglobin mutants. | Herold, S., et al. 2001. J Am Chem Soc. 123: 4085-6. PMID: 11457162
- Controlling ligand binding in myoglobin by mutagenesis. | Draghi, F., et al. 2002. J Biol Chem. 277: 7509-19. PMID: 11744723
- The iron-protein link in haemoglobin and myoglobin. | O'HAGAN, JE. 1959. Nature. 183: 393. PMID: 13632727
- Myoglobin clearance during acute continuous hemodiafiltration. | Bellomo, R., et al. 1991. Intensive Care Med. 17: 509. PMID: 1797903
- Quantitative turbidimetric assay for determining myoglobin evaluated. | Delanghe, J., et al. 1991. Ann Clin Biochem. 28 (Pt 5): 474-9. PMID: 1958050
- Serum myoglobin in patients with thyroid dysfunction. | Mula-Abed, WA., et al. 2009. Sultan Qaboos Univ Med J. 9: 37-41. PMID: 21509273
- Human myoglobin: preparation, quantitation and standardization. | Boesken, WH., et al. 1977. Res Exp Med (Berl). 171: 71-8. PMID: 410087
- Molecular cloning of seal myoglobin mRNA. | Wood, D., et al. 1982. Nucleic Acids Res. 10: 7133-44. PMID: 6185919
- Characterizing global substates of myoglobin. | Andrews, BK., et al. 1998. Structure. 6: 587-94. PMID: 9634696
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
myoglobin Antibody (8) | sc-130332 | 200 µg/ml | $322.00 | |||
myoglobin Antibody (8): m-IgG Fc BP-HRP Bundle | sc-537322 | 200 µg Ab; 10 µg BP | $361.00 | |||
myoglobin Antibody (8): m-IgGκ BP-HRP Bundle | sc-534562 | 200 µg Ab; 40 µg BP | $361.00 | |||
myoglobin Antibody (8): m-IgG1 BP-HRP Bundle | sc-545136 | 200 µg Ab; 20 µg BP | $361.00 |