MYH11 Antibody (V-10): sc-65735
- MYH11 Antibody (V-10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against crude smooth muscle extract from uterus myometrium of human origin
- recommended for detection of myosin heavy chain 11 isoforms SM-1 and SM-2 of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including and
- See MYH11 (G-4): sc-6956 for MYH11 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for MYH11 Antibody (V-10) for WB and IHC(P) applications. This reagent is now offered in a bundle with MYH11 Antibody (V-10) (see ordering information below).
MYH11 Antibody (V-10) is a mouse monoclonal IgG1 antibody that detects Myosin Heavy Chain 11 (MYH11) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. MYH11 monoclonal antibody (V-10) is raised against crude smooth muscle extract from uterus myometrium of human origin. MYH11 is primarily located in the contractile apparatus of smooth muscle cells, where precise positioning within the cytoskeleton is essential for interacting with actin filaments to generate force, enabling critical processes such as vascular contraction and gastrointestinal motility. Anti-MYH11 antibody (V-10) plays a crucial role in smooth muscle contraction, as MYH11 is a key component of the contractile apparatus, interacting with actin to facilitate muscle movement. MYH11′s structure consists of a hexameric assembly of two heavy chains and associated light chains, which are essential for motor function. MYH11 (V-10) monoclonal antibody recognizes heavy chains encoded by the MYH gene family that exhibit actin-activated ATPase activity, vital for generating force necessary for muscle contraction. Differential expression of MYH11 isoforms in various muscle types underscores significance in regulating contraction speed and muscle function. Anti-MYH11 antibody (V-10) serves as an invaluable tool for researchers studying smooth muscle physiology and related pathologies, providing insights into molecular mechanisms underlying muscle contraction and regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MYH11 Antibody (V-10) | sc-65735 | 200 µg/ml | $316.00 | |||
MYH11 Antibody (V-10): m-IgG Fc BP-HRP Bundle | sc-539192 | 200 µg Ab; 10 µg BP | $354.00 |