Myeloid Marker Antibody (BM-1): sc-59333
- Myeloid Marker Antibody (BM-1) is a mouse monoclonal IgG1 κ Myeloid Marker antibody provided at 200 µg/ml
- raised against peripheral blood mononuclear cells of human origin
- Myeloid Marker Antibody (BM-1) is recommended for detection of myeloid specific DNA binding protein in myeloid precursor cells and leukemias derived from them of human origin by IF and IHC(P)
- Anti-Myeloid Marker Antibody (BM-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Myeloid Marker Antibody (BM-1) for IHC(P) applications. These reagents are now offered in bundles with Myeloid Marker Antibody (BM-1) (see ordering information below).
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Myeloid Marker Antibody (BM-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Myeloid Marker protein of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Myeloid Marker monoclonal antibody (BM-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Myeloid cells, which originate in the bone marrow during hematopoiesis, play a crucial role in the immune response and are essential for the body′s defense against pathogens. These cells encompass all hematopoietic cells except for lymphoid cells, such as T cells, B cells, natural killer cells, and dendritic cells. Myeloid Marker (BM-1) antibody helps identify and differentiate myeloid lineage cells, which can further differentiate into various cell types, including vascular endothelial cells. This differentiation is vital for maintaining vascular integrity and responding to inflammatory signals. Additionally, Myeloid Marker expression can be instrumental in tracking certain diseases, such as Kawasaki disease, a self-limited vasculitis that affects multiple organs, including the skin, mucous membranes, lymph nodes, blood vessel walls, and heart. Myeloid Marker (BM-1) monoclonal antibody′s versatility in various applications makes this product an invaluable tool for researchers studying myeloid cell biology and related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Myeloid Marker Antibody (BM-1) References:
- Mast cell and myeloid marker expression during early in vitro mast cell differentiation from human peripheral blood mononuclear cells. | Welker, P., et al. 2000. J Invest Dermatol. 114: 44-50. PMID: 10620114
- Myeloid marker expression on antiviral CD8+ T cells following an acute virus infection. | Lin, Y., et al. 2003. Eur J Immunol. 33: 2736-43. PMID: 14515257
- Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells. | Fujiyama, S., et al. 2003. Circ Res. 93: 980-9. PMID: 14525810
- Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells. | Viemann, D., et al. 2005. Blood. 105: 2955-62. PMID: 15598812
- Myeloid lineage progenitors give rise to vascular endothelium. | Bailey, AS., et al. 2006. Proc Natl Acad Sci U S A. 103: 13156-61. PMID: 16920790
- Myeloid suppressor cells regulate the adaptive immune response to cancer. | Frey, AB. 2006. J Clin Invest. 116: 2587-90. PMID: 17016554
- Establishment, characterization and determination of cell surface sugar receptor (lectin) expression by neoglycoenzymes of a human myeloid marker-expressing B lymphoblastoid cell line. | Gabius, S., et al. 1991. Anticancer Res. 11: 793-800. PMID: 1712180
- Neuroendocrine, psychophysiological and subjective reactivity to an alcohol placebo in male alcoholic patients. | Dolinsky, ZS., et al. 1987. Alcohol Clin Exp Res. 11: 296-300. PMID: 3307497
- Expression of a myeloid marker on TdT-positive acute lymphocytic leukemic cells: evidence by double-fluorescence staining. | Bettelheim, P., et al. 1982. Blood. 60: 1392-6. PMID: 6182933
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myeloid Marker Antibody (BM-1) | sc-59333 | 200 µg/ml | $322.00 | |||
Myeloid Marker Antibody (BM-1): m-IgG Fc BP-HRP Bundle | sc-526929 | 200 µg Ab; 10 µg BP | $361.00 | |||
Myeloid Marker Antibody (BM-1): m-IgG1 BP-HRP Bundle | sc-532302 | 200 µg Ab; 20 µg BP | $361.00 | |||
Myeloid Marker Antibody (BM-1) AC | sc-59333 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Myeloid Marker Antibody (BM-1) HRP | sc-59333 HRP | 200 µg/ml | $322.00 | |||
Myeloid Marker Antibody (BM-1) FITC | sc-59333 FITC | 200 µg/ml | $336.00 | |||
Myeloid Marker Antibody (BM-1) PE | sc-59333 PE | 200 µg/ml | $349.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 488 | sc-59333 AF488 | 200 µg/ml | $364.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 546 | sc-59333 AF546 | 200 µg/ml | $364.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 594 | sc-59333 AF594 | 200 µg/ml | $364.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 647 | sc-59333 AF647 | 200 µg/ml | $364.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 680 | sc-59333 AF680 | 200 µg/ml | $364.00 | |||
Myeloid Marker Antibody (BM-1) Alexa Fluor® 790 | sc-59333 AF790 | 200 µg/ml | $364.00 |