MVD Antibody (2B5): sc-100559
- MVD Antibody (2B5) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant MVD of human origin
- recommended for detection of MVD of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MVD Antibody (2B5). This work is in progress.
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SEE ALSO...
MVD Antibody (2B5) is a mouse monoclonal IgG2a antibody that detects MVD in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MVD, or mevalonate (diphospho) decarboxylase, is a 400 amino acid protein that plays a pivotal role in the biosynthesis of isoprenoids, which are essential for various cellular functions, including the synthesis of cholesterol and other vital lipids. MVD is primarily located in the cytoplasm of cells in tissues such as the lung, liver, heart, skeletal muscle, brain, pancreas, placenta, and kidney, where MVD catalyzes the ATP-dependent conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate, a key precursor in cholesterol biosynthesis. MVD′s cellular location enables efficient facilitation of the early steps of cholesterol synthesis, which is critical for maintaining cellular membrane integrity and producing steroid hormones. Given MVD′s essential function in lipid metabolism, MVD may serve as a valuable target for therapeutic interventions aimed at managing cholesterol levels and related metabolic disorders. Anti-MVD antibody (2B5) is an excellent tool for researchers investigating the role of this enzyme in various biological processes and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MVD Antibody (2B5) | sc-100559 | 100 µg/ml | $339.00 |