Mucin 15/MUC15 Antibody (H-5): sc-365746
- Mucin 15/MUC15 Antibody (H-5) is a mouse monoclonal IgG1 κ Mucin 15/MUC15 antibody provided at 200 µg/ml
- raised against amino acids 23-232 mapping within an N-terminal extracellular domain of Mucin 15 of mouse origin
- Mucin 15/MUC15 Antibody (H-5) is recommended for detection of Mucin 15 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Mucin 15/MUC15 Antibody (H-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Mucin 15/MUC15 Antibody (H-5) for WB applications. These reagents are now offered in bundles with Mucin 15/MUC15 Antibody (H-5) (see ordering information below).
Mucin 15 Antibody (H-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects Mucin 15 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Mucin 15 (H-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Mucin 15 is a member of the mucin family, comprising highly glycosylated proteins that play critical roles in cell adhesion, signaling, and protection of epithelial cells. Mucin 15 is primarily located on the cell surface and within the extracellular matrix, where Mucin 15 contributes to forming a protective barrier against pathogens and particulate matter. Mucin 15 presence in various tissues, including prostate, testis, lung, spleen, thymus, ovary, small intestine, colon, bone marrow, lymph nodes, and peripheral blood leukocytes, underscores Mucin 15′s importance in maintaining mucosal integrity and facilitating cellular interactions. Mucin 15 is characterized by a variable number of tandem repeats, which can influence interactions with other proteins and overall function in cellular processes. Mucin 15′s ability to modulate adhesion to the extracellular matrix is particularly significant, as such modulation can impact cell migration and tissue repair mechanisms, making Mucin 15 a valuable target for research in cancer biology and regenerative medicine.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Mucin 15/MUC15 Antibody (H-5) References:
- Structural organization and classification of the human mucin genes. | Moniaux, N., et al. 2001. Front Biosci. 6: D1192-206. PMID: 11578969
- Mucin apoprotein expression in COPD. | Leikauf, GD., et al. 2002. Chest. 121: 166S-182S. PMID: 12010847
- Isolation and characterization of MUC15, a novel cell membrane-associated mucin. | Pallesen, LT., et al. 2002. Eur J Biochem. 269: 2755-63. PMID: 12047385
- Mucins and mucin binding proteins in colorectal cancer. | Byrd, JC. and Bresalier, RS. 2004. Cancer Metastasis Rev. 23: 77-99. PMID: 15000151
- Cloning and sequencing of a human pancreatic tumor mucin cDNA. | Lan, MS., et al. 1990. J Biol Chem. 265: 15294-9. PMID: 2394722
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mucin 15/MUC15 Antibody (H-5) | sc-365746 | 200 µg/ml | $322.00 | |||
Mucin 15/MUC15 Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-527396 | 200 µg Ab; 10 µg BP | $361.00 | |||
Mucin 15/MUC15 Antibody (H-5): m-IgG1 BP-HRP Bundle | sc-532769 | 200 µg Ab; 20 µg BP | $361.00 | |||
Mucin 15/MUC15 Antibody (H-5) AC | sc-365746 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Mucin 15/MUC15 Antibody (H-5) HRP | sc-365746 HRP | 200 µg/ml | $322.00 | |||
Mucin 15/MUC15 Antibody (H-5) FITC | sc-365746 FITC | 200 µg/ml | $336.00 | |||
Mucin 15/MUC15 Antibody (H-5) PE | sc-365746 PE | 200 µg/ml | $349.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 488 | sc-365746 AF488 | 200 µg/ml | $364.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 546 | sc-365746 AF546 | 200 µg/ml | $364.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 594 | sc-365746 AF594 | 200 µg/ml | $364.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 647 | sc-365746 AF647 | 200 µg/ml | $364.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 680 | sc-365746 AF680 | 200 µg/ml | $364.00 | |||
Mucin 15/MUC15 Antibody (H-5) Alexa Fluor® 790 | sc-365746 AF790 | 200 µg/ml | $364.00 |