µ-crystallin Antibody (F-11): sc-376687
- µ-crystallin Antibody (F-11) is a mouse monoclonal IgG2b κ µ-crystallin antibody, cited in 8 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 45-85 near the N-terminus of µ-crystallin of human origin
- µ-crystallin Antibody (F-11) is recommended for detection of µ-crystallin of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-µ-crystallin Antibody (F-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for µ-crystallin Antibody (F-11) for WB applications. These reagents are now offered in bundles with µ-crystallin Antibody (F-11) (see ordering information below).
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µ-crystallin Antibody (F-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects µ-crystallin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-µ-crystallin antibody (F-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. µ-crystallin (F-11) antibody targets a protein that plays a crucial role in binding NADPH and thyroid hormone, suggesting involvement in regulatory and developmental processes beyond structural functions in lens tissue. µ-crystallin (F-11) monoclonal antibody recognizes a protein encoded by a gene located on chromosome 16p13, expressed in neural tissue, muscle, and kidney, indicating diverse functional roles across different tissues. Unlike other crystallins primarily contributing to eye lens structural integrity, µ-crystallin′s unique binding properties position this protein as a key player in cellular signaling and metabolic regulation, making µ-crystallin an important target for research in developmental biology and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
µ-crystallin Antibody (F-11) References:
- Structure of the crystallins. | Slingsby, C. and Clout, NJ. 1999. Eye (Lond). 13 (Pt 3b): 395-402. PMID: 10627816
- Identification of zeta-crystallin/NADPH:quinone reductase as a renal glutaminase mRNA pH response element-binding protein. | Tang, A. and Curthoys, NP. 2001. J Biol Chem. 276: 21375-80. PMID: 11294877
- Alpha-crystallin. | Horwitz, J. 2003. Exp Eye Res. 76: 145-53. PMID: 12565801
- Localization of the human gene for mu-crystallin to chromosome 16p. | Chen, H., et al. 1992. Genomics. 14: 1115-6. PMID: 1478656
- Desminopathies in muscle disease. | Paulin, D., et al. 2004. J Pathol. 204: 418-27. PMID: 15495235
- Transparency and non-refractive functions of crystallins--a proposal. | Bhat, SP. 2004. Exp Eye Res. 79: 809-16. PMID: 15642317
- Lambda-crystallin, a major rabbit lens protein, is related to hydroxyacyl-coenzyme A dehydrogenases. | Mulders, JW., et al. 1988. J Biol Chem. 263: 15462-6. PMID: 3170592
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
µ-crystallin Antibody (F-11) | sc-376687 | 200 µg/ml | $322.00 | |||
µ-crystallin Antibody (F-11): m-IgGκ BP-HRP Bundle | sc-523047 | 200 µg Ab, 40 µg BP | $361.00 | |||
µ-crystallin Antibody (F-11): m-IgG2b BP-HRP Bundle | sc-549085 | 200 µg Ab; 10 µg BP | $361.00 | |||
μ-crystallin Antibody (F-11) AC | sc-376687 AC | 500 µg/ml, 25% agarose | $424.00 | |||
μ-crystallin Antibody (F-11) HRP | sc-376687 HRP | 200 µg/ml | $322.00 | |||
μ-crystallin Antibody (F-11) FITC | sc-376687 FITC | 200 µg/ml | $336.00 | |||
μ-crystallin Antibody (F-11) PE | sc-376687 PE | 200 µg/ml | $349.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 488 | sc-376687 AF488 | 200 µg/ml | $364.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 546 | sc-376687 AF546 | 200 µg/ml | $364.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 594 | sc-376687 AF594 | 200 µg/ml | $364.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 647 | sc-376687 AF647 | 200 µg/ml | $364.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 680 | sc-376687 AF680 | 200 µg/ml | $364.00 | |||
μ-crystallin Antibody (F-11) Alexa Fluor® 790 | sc-376687 AF790 | 200 µg/ml | $364.00 | |||
μ-crystallin (F-11) Neutralizing Peptide | sc-376687 P | 100 µg/0.5 ml | $69.00 |