MS4A7 Antibody (SW-44): sc-134394

MS4A7 Antibody (SW-44) is a mouse monoclonal IgG2b kappa light chain antibody that detects MS4A7 of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MS4A7 antibody (SW-44) is available as a non-conjugated format. MS4A7, also known as Membrane-spanning 4-domains subfamily A member 7, is a 240 amino acid multi-pass membrane protein that plays a crucial role in signal transduction, primarily due to the presence of multiple phosphorylation sites on its C-terminus. These phosphorylation sites are essential for modulating MS4A7 activity and interactions, influencing various cellular processes such as proliferation and differentiation. The MS4A family, which includes at least 26 members in both mouse and human, is characterized by four highly conserved transmembrane domains and is involved in the formation of oligomeric cell surface complexes that facilitate signal transduction across diverse cell types. Understanding MS4A7 function and interactions is vital for elucidating MS4A7 role in immune responses and potential implications in diseases, making MS4A7 (SW-44) monoclonal antibody a valuable tool for researchers studying these pathways.

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MS4A7 Antibody (SW-44) References:

1. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.  |  Ishibashi, K., et al. 2001. Gene. 264: 87-93. PMID: 11245982
2. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse.  |  Liang, Y. and Tedder, TF. 2001. Genomics. 72: 119-27. PMID: 11401424
3. Structural organization of the human MS4A gene cluster on Chromosome 11q12.  |  Liang, Y., et al. 2001. Immunogenetics. 53: 357-68. PMID: 11486273
4. CFFM4: a new member of the CD20/FcepsilonRIbeta family.  |  Gingras, MC., et al. 2001. Immunogenetics. 53: 468-76. PMID: 11685457
5. Complete sequencing and characterization of 21,243 full-length human cDNAs.  |  Ota, T., et al. 2004. Nat Genet. 36: 40-5. PMID: 14702039
6. The origins of human embryonic stem cells: a biological conundrum.  |  Brink, TC., et al. 2008. Cells Tissues Organs. 188: 9-22. PMID: 18160822