MRP-S6 Antibody (E-8): sc-390597
- MRP-S6 Antibody (E-8) is a mouse monoclonal IgG1 κ MRP-S6 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 11-125 mapping at the C-terminus of MRP-S6 of human origin
- MRP-S6 Antibody (E-8) is recommended for detection of MRP-S6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-MRP-S6 Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MRP-S6 Antibody (E-8) for WB and IHC(P) applications. These reagents are now offered in bundles with MRP-S6 Antibody (E-8) (see ordering information below).
MRP-S6 Antibody (E-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects MRP-S6 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). MRP-S6 (E-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MRP-S6, or mitochondrial ribosomal protein S6, plays a crucial role in mitochondrial protein synthesis, as MRP-S6 is a key component of the mitochondrial ribosome′s small subunit (28S), which consists of 12S rRNA and nearly 30 distinct proteins. The unique structure of mitochondrial ribosomes, which are composed of a higher proportion of protein compared to prokaryotic ribosomes, is essential for their function in translating mitochondrial mRNA into proteins that are vital for cellular respiration and energy production. Notably, MRP-S6 shares homology with ribosomal proteins found in Escherichia coli, highlighting the evolutionary conservation of mitochondrial ribosomal components across species. This conservation underscores the importance of MRP-S6 in maintaining mitochondrial function and overall cellular health, making MRP-S6 a significant target for research in mitochondrial biology and related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MRP-S6 Antibody (E-8) References:
- The nuclear-encoded SDH2-RPS14 precursor is proteolytically processed between SDH2 and RPS14 to generate maize mitochondrial RPS14. | Figueroa, P., et al. 2000. Biochem Biophys Res Commun. 271: 380-5. PMID: 10799306
- A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. | Koc, EC., et al. 2000. J Biol Chem. 275: 32585-91. PMID: 10938081
- The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. | Cavdar Koc, E., et al. 2001. J Biol Chem. 276: 19363-74. PMID: 11279123
- The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. | Kenmochi, N., et al. 2001. Genomics. 77: 65-70. PMID: 11543634
- Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. | Zhang, Z. and Gerstein, M. 2003. Genomics. 81: 468-80. PMID: 12706105
- [Topography of ribosomal proteins: reconsideration of of protein map of small ribosomal subunit]. | Spirin, AS., et al. 1996. Biokhimiia. 61: 1928-30. PMID: 9004854
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRP-S6 Antibody (E-8) | sc-390597 | 200 µg/ml | $316.00 | |||
MRP-S6 Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-530199 | 200 µg Ab; 10 µg BP | $354.00 | |||
MRP-S6 Antibody (E-8): m-IgGκ BP-HRP Bundle | sc-523597 | 200 µg Ab, 40 µg BP | $354.00 | |||
MRP-S6 Antibody (E-8): m-IgG1 BP-HRP Bundle | sc-543923 | 200 µg Ab; 20 µg BP | $354.00 | |||
MRP-S6 Antibody (E-8) AC | sc-390597 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MRP-S6 Antibody (E-8) HRP | sc-390597 HRP | 200 µg/ml | $316.00 | |||
MRP-S6 Antibody (E-8) FITC | sc-390597 FITC | 200 µg/ml | $330.00 | |||
MRP-S6 Antibody (E-8) PE | sc-390597 PE | 200 µg/ml | $343.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 488 | sc-390597 AF488 | 200 µg/ml | $357.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 546 | sc-390597 AF546 | 200 µg/ml | $357.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 594 | sc-390597 AF594 | 200 µg/ml | $357.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 647 | sc-390597 AF647 | 200 µg/ml | $357.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 680 | sc-390597 AF680 | 200 µg/ml | $357.00 | |||
MRP-S6 Antibody (E-8) Alexa Fluor® 790 | sc-390597 AF790 | 200 µg/ml | $357.00 |