MRP-S28 Antibody (F-9): sc-398572
- MRP-S28 Antibody (F-9) is a mouse monoclonal IgG1 κ MRP-S28 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 78-96 within an internal region of MRP-S28 of human origin
- MRP-S28 Antibody (F-9) is recommended for detection of MRP-S28 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MRP-S28 Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MRP-S28 Antibody (F-9) for WB applications. These reagents are now offered in bundles with MRP-S28 Antibody (F-9) (see ordering information below).
MRP-S28 Antibody (F-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects MRP-S28 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MRP-S28 Antibody (F-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MRP-S28, also known as mitochondrial 28S ribosomal protein S28 or S28mt, is a crucial component of the mitochondrial ribosome, specifically located in the 28S subunit, which plays a vital role in protein synthesis within mitochondria. The unique structure of MRP-S28, comprising 187 amino acids, is essential for proper assembly and function of the mitoribosome, as MRP-S28 contributes to the ribosomal architecture that facilitates translation of mitochondrial mRNA into proteins necessary for cellular respiration and energy production. Given that mitochondrial dysfunction is implicated in various diseases, including neurodegenerative disorders and metabolic syndromes, accurate detection and study of MRP-S28 is critical for understanding mitochondrial biology and potential therapeutic interventions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MRP-S28 Antibody (F-9) References:
- A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. | Koc, EC., et al. 2000. J Biol Chem. 275: 32585-91. PMID: 10938081
- Characterization of long cDNA clones from human adult spleen. | Hattori, A., et al. 2000. DNA Res. 7: 357-66. PMID: 11214971
- The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. | Cavdar Koc, E., et al. 2001. J Biol Chem. 276: 19363-74. PMID: 11279123
- The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. | Kenmochi, N., et al. 2001. Genomics. 77: 65-70. PMID: 11543634
- Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. | Zhang, Z. and Gerstein, M. 2003. Genomics. 81: 468-80. PMID: 12706105
- Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. | Scanlan, MJ., et al. 2001. Cancer Immun. 1: 4. PMID: 12747765
- ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA. | Ishiguchi, H., et al. 2004. Int J Cancer. 111: 900-9. PMID: 15300802
- Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. | Goldschmidt-Reisin, S., et al. 1998. J Biol Chem. 273: 34828-36. PMID: 9857009
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRP-S28 Antibody (F-9) | sc-398572 | 200 µg/ml | $316.00 | |||
MRP-S28 Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-530847 | 200 µg Ab; 10 µg BP | $354.00 | |||
MRP-S28 Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-524395 | 200 µg Ab, 40 µg BP | $354.00 | |||
MRP-S28 Antibody (F-9): m-IgG1 BP-HRP Bundle | sc-544277 | 200 µg Ab; 20 µg BP | $354.00 | |||
MRP-S28 Antibody (F-9) AC | sc-398572 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MRP-S28 Antibody (F-9) HRP | sc-398572 HRP | 200 µg/ml | $316.00 | |||
MRP-S28 Antibody (F-9) FITC | sc-398572 FITC | 200 µg/ml | $330.00 | |||
MRP-S28 Antibody (F-9) PE | sc-398572 PE | 200 µg/ml | $343.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 488 | sc-398572 AF488 | 200 µg/ml | $357.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 546 | sc-398572 AF546 | 200 µg/ml | $357.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 594 | sc-398572 AF594 | 200 µg/ml | $357.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 647 | sc-398572 AF647 | 200 µg/ml | $357.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 680 | sc-398572 AF680 | 200 µg/ml | $357.00 | |||
MRP-S28 Antibody (F-9) Alexa Fluor® 790 | sc-398572 AF790 | 200 µg/ml | $357.00 | |||
MRP-S28 (F-9) Neutralizing Peptide | sc-398572 P | 100 µg/0.5 ml | $68.00 |