MRP-L44 Antibody (E-7): sc-515489

MRP-L44 Antibody (E-7) is a mouse monoclonal IgG3 antibody that detects MRP-L44 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MRP-L44, a 332 amino acid protein, plays a crucial role in mitochondrial protein synthesis as a component of the large 39S ribosomal subunit, which is essential for proper mitochondrial function. MRP-L44 localization within the mitochondrion ensures protein synthesis occurs close to the site of action, facilitating efficient energy production and metabolic processes. Additionally, MRP-L44 features one RNase III domain and one double-stranded RNA-binding motif, which are critical for RNA maturation and localization, further underscoring MRP-L44′s significance in mitochondrial function. The gene encoding MRP-L44 is located on human chromosome 2, a region containing over 1,400 genes and representing nearly 8% of the human genome, highlighting the complexity and importance of the genetic landscape. MRP-L44 (E-7) antibody serves as an invaluable tool for researchers studying mitochondrial biology and protein synthesis within these organelles.

The preferred MRP-L44 antibody is MRP-L44 Antibody (G-12): sc-515503.