MREG Antibody (E-4): sc-374217
- MREG Antibody (E-4) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 1-214 representing full length MREG of human origin
- recommended for detection of MREG of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MREG Antibody (E-4) for WB applications. These reagents are now offered in bundles with MREG Antibody (E-4) (see ordering information below).
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SEE ALSO...
MREG Antibody (E-4) is a mouse monoclonal IgG2a antibody that detects MREG in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MREG, or melanoregulin, is a crucial protein involved in the biogenesis of disk membranes in photoreceptor rod cells, which are essential for vision in low-light conditions. MREG (E-4) antibody targets proteins located in the outer segment of rod cells, where MREG plays a vital role in membrane fusion and renewal of disk membranes, ensuring continuous functionality of photoreceptors. MREG interacts with RDS (Peripherin-2), a tetraspanin protein critical for maintaining structural integrity of photoreceptor cells during membrane renewal. MREG′s location in the outer segment directly influences phototransduction efficiency and overall visual acuity. MREG consists of 214 amino acids and is expressed in two isoforms due to alternative splicing, highlighting complexity and potential for diverse regulatory roles within photoreceptor cells. Anti-MREG antibody (E-4) serves as an invaluable tool for researchers studying retinal biology and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MREG Antibody (E-4) | sc-374217 | 200 µg/ml | $322.00 | |||
MREG Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-537937 | 200 µg Ab; 10 µg BP | $361.00 | |||
MREG Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-535422 | 200 µg Ab; 40 µg BP | $361.00 |