Date published: 2026-5-2

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MREG Antibody (A-6): sc-374144

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Datasheets
  • MREG Antibody (A-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 1-214 representing full length MREG of human origin
  • MREG Antibody (A-6) is recommended for detection of MREG of mouse, rat, human origin by WB, IP, IF and ELISA
  • Anti-MREG Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MREG Antibody (A-6) for WB applications. These reagents are now offered in bundles with MREG Antibody (A-6) (see ordering information below).
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    MREG Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects MREG in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MREG antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MREG, or melanoregulin, is a crucial protein involved in the biogenesis of disk membranes in photoreceptor rod cells, which are essential for vision in low-light conditions. The rod outer segment, composed of stacked arrays of disk membranes, undergoes constant renewal through complex biochemical processes, and MREG facilitates membrane fusion during this renewal. Additionally, MREG interacts with RDS (Peripherin-2), a tetraspanin protein vital for maintaining the structural integrity of photoreceptor cells during the membrane fusion process. MREG consists of 214 amino acids and is expressed in photoreceptor cells, existing in two isoforms due to alternative splicing, highlighting functional diversity and importance in visual phototransduction.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    MREG Antibody (A-6)

    sc-374144
    200 µg/ml
    $322.00

    MREG Antibody (A-6): m-IgG Fc BP-HRP Bundle

    sc-529672
    200 µg Ab; 10 µg BP
    $361.00

    MREG Antibody (A-6): m-IgGκ BP-HRP Bundle

    sc-522637
    200 µg Ab, 40 µg BP
    $361.00

    MREG Antibody (A-6): m-IgG1 BP-HRP Bundle

    sc-543630
    200 µg Ab; 20 µg BP
    $361.00

    MREG Antibody (A-6) AC

    sc-374144 AC
    500 µg/ml, 25% agarose
    $424.00

    MREG Antibody (A-6) HRP

    sc-374144 HRP
    200 µg/ml
    $322.00

    MREG Antibody (A-6) FITC

    sc-374144 FITC
    200 µg/ml
    $336.00

    MREG Antibody (A-6) PE

    sc-374144 PE
    200 µg/ml
    $349.00

    MREG Antibody (A-6) Alexa Fluor® 488

    sc-374144 AF488
    200 µg/ml
    $364.00

    MREG Antibody (A-6) Alexa Fluor® 546

    sc-374144 AF546
    200 µg/ml
    $364.00

    MREG Antibody (A-6) Alexa Fluor® 594

    sc-374144 AF594
    200 µg/ml
    $364.00

    MREG Antibody (A-6) Alexa Fluor® 647

    sc-374144 AF647
    200 µg/ml
    $364.00

    MREG Antibody (A-6) Alexa Fluor® 680

    sc-374144 AF680
    200 µg/ml
    $364.00

    MREG Antibody (A-6) Alexa Fluor® 790

    sc-374144 AF790
    200 µg/ml
    $364.00

    What is the recommended starting dilution for Western blot for MREG (A-6): sc-374144 monoclonal antibody?

    Asked by: Randy McDonald
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-374144.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2026, m_4, d_29, h_11CST
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    Rated 5 out of 5 by from Produced positive Western Blot data of MREGProduced positive Western Blot data of MREG expression in non-transfected 293T, human MREG transfected 293T, MCF7, CCRF-CEM and DU 145 whole cell lysates. -SCBT QC
    Date published: 2014-12-14
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    MREG Antibody (A-6) is rated 5.0 out of 5 by 1.
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