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MPP3 Antibody (PZ-2D21) is a mouse monoclonal IgG1 antibody that detects MPP3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein that belongs to the MAGUK family, which plays a crucial role in regulating cell proliferation, intracellular junctions, and signaling pathways by interacting with the cytoskeleton. The structure of MPP3 contains a guanylate kinase-like domain, a PDZ domain, two L27 domains, and an SH3 domain, which facilitate interactions with other proteins. The PDZ domain of MPP3 allows binding to the C-terminus of TSLC1, a protein involved in cell adhesion and signaling, thereby influencing cellular processes. MPP3 has been shown to interact with other proteins such as SR-2A and SR-4, further underscoring MPP3′s significance in cellular dynamics. Anti-MPP3 antibody (PZ-2D21) serves as an essential tool for researchers exploring the functional roles of MPP3 in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MPP3 Antibody (PZ-2D21) | sc-134390 | 100 µg/ml | $333.00 |