MPHOSPH6 Antibody (D-3): sc-393429
- MPHOSPH6 Antibody (D-3) is a mouse monoclonal IgG1 κ MPHOSPH6 antibody provided at 200 µg/ml
- raised against amino acids 39-129 mapping within an internal region of MPHOSPH6 of human origin
- MPHOSPH6 Antibody (D-3) is recommended for detection of MPHOSPH6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-MPHOSPH6 Antibody (D-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MPHOSPH6 (D-3): sc-393429.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MPHOSPH6 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with MPHOSPH6 Antibody (D-3) (see ordering information below).
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MPHOSPH6 Antibody (D-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects MPHOSPH6 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-MPHOSPH6 antibody (D-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MPHOSPH6, also known as M-phase phosphoprotein 6 or MPP6, plays a crucial role in regulating cell cycle progression, particularly during the transition from interphase to mitosis. MPHOSPH6 is involved in phosphorylating various substrates, essential for interphase structure disassembly and M phase-specific enzymatic activity activation. MPHOSPH6 is encoded by a gene located on human chromosome 16q23.3 and mouse chromosome 8 E1, consisting of 160 amino acids with a nuclear localization signal motif that facilitates nuclear transport. Proper MPHOSPH6 function is vital for cell division, and dysregulation can lead to various cellular abnormalities, making MPHOSPH6 an important target for research in cancer and other proliferative diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MPHOSPH6 Antibody (D-3) References:
- AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. | Chen, CY., et al. 2001. Cell. 107: 451-64. PMID: 11719186
- Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. | Leonoudakis, D., et al. 2004. J Biol Chem. 279: 22331-46. PMID: 15024025
- A protein interaction framework for human mRNA degradation. | Lehner, B. and Sanderson, CM. 2004. Genome Res. 14: 1315-23. PMID: 15231747
- MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation. | Schilders, G., et al. 2005. Nucleic Acids Res. 33: 6795-804. PMID: 16396833
- C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing. | Schilders, G., et al. 2007. Nucleic Acids Res. 35: 2564-72. PMID: 17412707
- Identification of novel M phase phosphoproteins by expression cloning. | Matsumoto-Taniura, N., et al. 1996. Mol Biol Cell. 7: 1455-69. PMID: 8885239
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MPHOSPH6 Antibody (D-3) | sc-393429 | 200 µg/ml | $316.00 | |||
MPHOSPH6 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-530455 | 200 µg Ab; 10 µg BP | $354.00 | |||
MPHOSPH6 Antibody (D-3): m-IgGκ BP-HRP Bundle | sc-523944 | 200 µg Ab, 40 µg BP | $354.00 | |||
MPHOSPH6 Antibody (D-3): m-IgG1 BP-HRP Bundle | sc-544059 | 200 µg Ab; 20 µg BP | $354.00 | |||
MPHOSPH6 Antibody (D-3) AC | sc-393429 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MPHOSPH6 Antibody (D-3) HRP | sc-393429 HRP | 200 µg/ml | $316.00 | |||
MPHOSPH6 Antibody (D-3) FITC | sc-393429 FITC | 200 µg/ml | $330.00 | |||
MPHOSPH6 Antibody (D-3) PE | sc-393429 PE | 200 µg/ml | $343.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 488 | sc-393429 AF488 | 200 µg/ml | $357.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 546 | sc-393429 AF546 | 200 µg/ml | $357.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 594 | sc-393429 AF594 | 200 µg/ml | $357.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 647 | sc-393429 AF647 | 200 µg/ml | $357.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 680 | sc-393429 AF680 | 200 µg/ml | $357.00 | |||
MPHOSPH6 Antibody (D-3) Alexa Fluor® 790 | sc-393429 AF790 | 200 µg/ml | $357.00 |