MPHOSPH6 Antibody (A-9): sc-377481

MPHOSPH6 Antibody (A-9) is a mouse monoclonal IgG2b antibody that detects MPHOSPH6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MPHOSPH6, also known as M-phase phosphoprotein 6, is a crucial 160 amino acid protein that plays a significant role in the regulation of cell cycle progression, particularly during the transition from interphase to mitosis. This protein is encoded by a gene located on human chromosome 16q23.3 and mouse chromosome 8 E1, and is a member of the MPP6 family, characterized by the presence of a nuclear localization signal motif that facilitates transport into the nucleus. The localization of MPHOSPH6 within the nucleus is vital for function, as MPHOSPH6 is involved in the phosphorylation of various substrates that are essential for the disassembly of interphase structures and the activation of mitotic processes. By understanding the role of MPHOSPH6 in cell cycle regulation, researchers can gain insights into the mechanisms underlying cell division and implications in cancer biology, where dysregulation of these processes can lead to tumorigenesis. Anti-MPHOSPH6 antibody (A-9) is an invaluable tool for scientists studying cell cycle dynamics and related pathways.

The preferred MPHOSPH6 antibody is MPHOSPH6 Antibody (D-3): sc-393429.