MOX-2 Antibody (A-8): sc-376748
- MOX-2 Antibody (A-8) is a mouse monoclonal IgG2a κ MOX-2 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 94-188 mapping within an internal region of MOX-2 of human origin
- MOX-2 Antibody (A-8) is recommended for detection of MOX-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- Anti-MOX-2 Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-376748 X, 200 µg/0.1 ml)
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MOX-2 Antibody (A-8) for WB applications. These reagents are now offered in bundles with MOX-2 Antibody (A-8) (see ordering information below).
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MOX-2 Antibody (A-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects MOX-2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MOX-2 (A-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MOX-2, also known as mesenchyme homeobox 2 or GAX, plays a crucial role in axial skeleton development, particularly in regulating myogenic genes essential for normal appendicular muscle formation. While MOX-2 is not required for myogenic precursor migration into the limb bud, MOX-2 expression is vital for differentiating these precursors into functional muscle tissue. Additionally, the human MEOX2 gene, which encodes MOX-2, is located on chromosome 7p21.1, and mutations in this gene have been associated with craniofacial and skeletal abnormalities. MOX-2 is expressed in placental tissue and is part of a homeobox protein family that includes MOX-1, which interacts with Pax-1, while MOX-2 preferentially associates with Pax-3, highlighting MOX-2′s importance in early mesoderm formation during gastrulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MOX-2 Antibody (A-8) References:
- Mox2 is a component of the genetic hierarchy controlling limb muscle development. | Mankoo, BS., et al. 1999. Nature. 400: 69-73. PMID: 10403250
- The homeobox genes MSX2 and MOX2 are candidates for regulating epithelial-mesenchymal cell interactions in the human placenta. | Quinn, LM., et al. 2000. Placenta. 21 Suppl A: S50-4. PMID: 10831122
- Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors. | Stamataki, D., et al. 2001. FEBS Lett. 499: 274-8. PMID: 11423130
- Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. | Candia, AF., et al. 1992. Development. 116: 1123-36. PMID: 1363541
- Differential localization of Mox-1 and Mox-2 proteins indicates distinct roles during development. | Candia, AF. and Wright, CV. 1996. Int J Dev Biol. 40: 1179-84. PMID: 9032023
- The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. | Stelnicki, EJ., et al. 1997. Differentiation. 62: 33-41. PMID: 9373945
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MOX-2 Antibody (A-8) | sc-376748 | 200 µg/ml | $322.00 | |||
MOX-2 Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-523079 | 200 µg Ab, 40 µg BP | $361.00 | |||
MOX-2 Antibody (A-8): m-IgG2a BP-HRP Bundle | sc-546141 | 200 µg Ab; 10 µg BP | $361.00 | |||
MOX-2 Antibody (A-8) X | sc-376748 X | 200 µg/0.1 ml | $322.00 | |||
MOX-2 Antibody (A-8) AC | sc-376748 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MOX-2 Antibody (A-8) HRP | sc-376748 HRP | 200 µg/ml | $322.00 | |||
MOX-2 Antibody (A-8) FITC | sc-376748 FITC | 200 µg/ml | $336.00 | |||
MOX-2 Antibody (A-8) PE | sc-376748 PE | 200 µg/ml | $349.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 488 | sc-376748 AF488 | 200 µg/ml | $364.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 546 | sc-376748 AF546 | 200 µg/ml | $364.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 594 | sc-376748 AF594 | 200 µg/ml | $364.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 647 | sc-376748 AF647 | 200 µg/ml | $364.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 680 | sc-376748 AF680 | 200 µg/ml | $364.00 | |||
MOX-2 Antibody (A-8) Alexa Fluor® 790 | sc-376748 AF790 | 200 µg/ml | $364.00 |