Moesin Antibody (38): sc-136268
- Moesin Antibody (38) is a mouse monoclonal IgG1, cited in 4 publications, provided at 50 µg/0.5 ml
- raised against amino acids 554-564 of Moesin of human origin
- recommended for detection of Moesin of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including canine
- See Moesin (E-10): sc-13122 for Moesin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Moesin Antibody (38). This work is in progress.
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Moesin Antibody (38) is a mouse monoclonal IgG1 antibody that detects Moesin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Moesin is a crucial member of the ezrin-radixin-moesin (ERM) protein family, which plays a vital role in linking the cytoskeleton to the plasma membrane, thereby influencing cell shape, motility, and signaling. Moesin is primarily localized at the cell cortex, where Moesin acts as a scaffold to facilitate interactions between actin filaments and membrane proteins, which is essential for maintaining cellular integrity and facilitating cellular responses to external stimuli. Notably, Moesin undergoes phosphorylation at specific sites, which modulates activity and interactions with other proteins, allowing for dynamic regulation of cellular processes. Moesin′s ability to interact with various signaling molecules, including those involved in cell adhesion and migration, underscores importance in processes such as tissue remodeling and immune responses. Anti-Moesin antibody (38) is an invaluable tool for researchers studying the intricate roles of Moesin in cellular dynamics and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Moesin Antibody (38) References:
- Moesin, a new cytoskeletal protein and constituent of filopodia: its role in cellular functions. | Furthmayr, H., et al. 1992. Kidney Int. 41: 665-70. PMID: 1573844
- Ezrin, Radixin and Moesin: key regulators of membrane-cortex interactions and signaling. | Neisch, AL. and Fehon, RG. 2011. Curr Opin Cell Biol. 23: 377-82. PMID: 21592758
- Moesin functionality in hypothermic liver preservation injury. | Tian, T., et al. 2014. Cryobiology. 69: 34-40. PMID: 24836372
- The ezrin-radixin-moesin family of proteins in the regulation of B-cell immune response. | Pore, D. and Gupta, N. 2015. Crit Rev Immunol. 35: 15-31. PMID: 25746045
- Moesin and myosin IIA modulate phagolysosomal biogenesis in macrophages. | Gomez, CP. and Descoteaux, A. 2018. Biochem Biophys Res Commun. 495: 1964-1971. PMID: 29247647
- A biophysical perspective of the regulatory mechanisms of ezrin/radixin/moesin proteins. | Senju, Y. and Tsai, FC. 2022. Biophys Rev. 14: 199-208. PMID: 35340609
- Moesin Serves as Scaffold Protein for PD-L1 in Human Uterine Cervical Squamous Carcinoma Cells. | Doukuni, R., et al. 2022. J Clin Med. 11: PMID: 35807113
- Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions. | Li, B., et al. 2022. Cell Signal. 100: 110466. PMID: 36100057
- Multiomics-based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis. | Li, J., et al. 2023. Clin Transl Med. 13: e1360. PMID: 37531302
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Moesin Antibody (38) | sc-136268 | 50 µg/0.5 ml | $322.00 |