MMP-3 Antibody (F-1): sc-271230
- MMP-3 Antibody (F-1) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 443-476 at the C-terminus (h) of MMP-3 of human origin
- recommended for detection of MKP-3 of mouse, rat and human origin by WB, IP, IF and ELISA
- See MMP-3 (1B4): sc-21732 for MMP-3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MMP-3 Antibody (F-1) for WB applications. These reagents are now offered in bundles with MMP-3 Antibody (F-1) (see ordering information below).
MMP-3 Antibody (F-1) is a mouse monoclonal IgG1 antibody that detects matrix metalloproteinase-3 (MMP-3) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MMP-3 plays a crucial role in the remodeling of the extracellular matrix by degrading various components, including collagen and proteoglycans, which is vital for processes such as tissue repair and development. Anti-MMP-3 antibody (F-1) activates procollagenase through both direct and indirect pathways, highlighting its importance in regulating collagen turnover, particularly in pathological conditions like cancer and inflammation. MMP-3 is expressed in various tissues, including the small intestine, lung, and heart, and its expression in stromal cells of breast carcinomas underscores its potential role in tumor progression and metastasis. MMP-3 (F-1) antibody serves as an essential tool for researchers investigating the dynamics of extracellular matrix remodeling and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MMP-3 Antibody (F-1) | sc-271230 | 200 µg/ml | $316.00 | |||
MMP-3 Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-540217 | 200 µg Ab; 10 µg BP | $354.00 | |||
MMP-3 Antibody (F-1): m-IgG1 BP-HRP Bundle | sc-541977 | 200 µg Ab; 20 µg BP | $354.00 | |||
MMP-3 (F-1) Neutralizing Peptide | sc-271230 P | 100 µg/0.5 ml | $68.00 |