Mitotic Cells Antibody (8B3G): sc-53006

Mitotic Cells Antibody (8B3G) is a mouse monoclonal IgM kappa light chain antibody that detects the Mitotic Cells protein of human origin by immunofluorescence (IF) and flow cytometry (FCM). Anti-Mitotic Cells antibody (8B3G) is available as the non-conjugated form, providing researchers with a reliable tool for studying cell division. Mitotic Cells (8B3G) antibody enables investigation of this protein′s crucial role in cell cycle regulation, particularly during M phase, where Mitotic Cells protein ensures accurate chromosome segregation into daughter cells. This process maintains genomic stability and prevents aneuploidy, which can lead to various diseases, including cancer. Mitotic Cells protein function involves interactions with key regulatory proteins, such as cyclins and cyclin-dependent kinases, which orchestrate cell cycle progression. Mitotic Cells (8B3G) monoclonal antibody helps researchers gain insights into cell division dynamics and mechanisms governing cellular proliferation, making this antibody essential for cancer biology and developmental research.

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Mitotic Cells Antibody (8B3G) References:

1. Chromosome condensation factor Brn1p is required for chromatid separation in mitosis.  |  Ouspenski, II., et al. 2000. Mol Biol Cell. 11: 1305-13. PMID: 10749931
2. Plasma membrane-cell wall connections: roles in mitosis and cytokinesis revealed by plasmolysis of Tradescantia virginiana leaf epidermal cells.  |  Cleary, AL. 2001. Protoplasma. 215: 21-34. PMID: 11732060
3. S-phase checkpoint controls mitosis via an APC-independent Cdc20p function.  |  Clarke, DJ., et al. 2003. Nat Cell Biol. 5: 928-35. PMID: 14502293
4. Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.  |  Rape, M. and Kirschner, MW. 2004. Nature. 432: 588-95. PMID: 15558010
5. Chromosome condensation outside of mitosis: mechanisms and new tools.  |  Gotoh, E. and Durante, M. 2006. J Cell Physiol. 209: 297-304. PMID: 16810672
6. Chromosome condensation in mitosis.  |  Matthews, HR. 1980. J Theor Biol. 83: 367-8. PMID: 7401665
7. Existence of a commitment program for mitosis in early G1 in tumour cells.  |  Larsson, O. and Zetterberg, A. 1995. Cell Prolif. 28: 33-43. PMID: 7833384
8. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.  |  Brandeis, M. and Hunt, T. 1996. EMBO J. 15: 5280-9. PMID: 8895573
9. Phosphorylation of protein-tyrosine phosphatase PTP-1B on identical sites suggests activation of a common signaling pathway during mitosis and stress response in mammalian cells.  |  Shifrin, VI., et al. 1997. J Biol Chem. 272: 2957-62. PMID: 9006942

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Mitotic Cells Antibody (8B3G) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Mitotic Cells Antibody (8B3G) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Mitotic Cells Antibody (8B3G) Specifications

Alternate Product Name: Mitotic Cells

Product Clone Name: 8B3G

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: Mitotic Cells

Epitope Species: human

Product Reactivity/Detection: mitotic cells

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: zebrafish

Applications: IF, FCM

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Mitotic Cells Antibody (8B3G): N/A