Date published: 2026-6-1

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Mitotic Cells Activators

The category of Mitotic Cells Activators encompasses a group of compounds or molecules that play a role in regulating or modulating the processes associated with mitosis, which is a critical stage of the cell cycle. Mitosis is the cellular process by which a single eukaryotic cell divides into two identical daughter cells, each with the same genetic information as the parent cell. It is a tightly regulated and highly coordinated series of events that involves the duplication and separation of chromosomes, ensuring the accurate distribution of genetic material to daughter cells. Mitotic Cells Activators are substances that can influence and impact various stages of mitosis, such as the initiation of mitotic entry, spindle formation, chromosome condensation, alignment, segregation, and cytokinesis.

These activators can have diverse effects on mitotic cells, including the acceleration or deceleration of cell division, the promotion of chromosome stability or instability, and the modulation of checkpoint mechanisms that monitor the fidelity of mitosis. Researchers use Mitotic Cells Activators to explore the intricate molecular and cellular processes underlying cell division and to dissect the signaling pathways and molecular players involved in mitosis regulation. Understanding how these activators function in mitotic cells is essential for gaining insights into fundamental biological processes, including tissue development, growth, repair, and maintenance, as well as for elucidating the molecular mechanisms that drive diseases associated with mitotic dysregulation, such as cancer.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Paclitaxel stabilizes microtubules and prevents their disassembly, affecting mitotic spindle dynamics and potentially upregulating mitotic proteins.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$102.00
$235.00
$459.00
$1749.00
$2958.00
4
(0)

Vinblastine binds to tubulin, inhibiting microtubule assembly and thus impacting mitotic spindle proteins and cell division.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$51.00
$231.00
$523.00
63
(1)

Etoposide inhibits DNA topoisomerase II, causing DNA damage and potentially influencing the expression of proteins in response to cell cycle checkpoints.

Aphidicolin

38966-21-1sc-201535
sc-201535A
sc-201535B
1 mg
5 mg
25 mg
$84.00
$306.00
$1104.00
30
(3)

Aphidicolin is a specific inhibitor of DNA polymerase, which can arrest cells in the S-phase and indirectly affect mitotic protein expression.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Methotrexate is a dihydrofolate reductase inhibitor, disrupting DNA synthesis and potentially affecting the regulation of the cell cycle and mitotic protein expression.

Roscovitine

186692-46-6sc-24002
sc-24002A
1 mg
5 mg
$94.00
$265.00
42
(2)

Roscovitine is a CDK inhibitor, and by inhibiting these kinases, it can affect cell cycle progression and the expression of mitotic proteins.

BI6727

755038-65-4sc-364432
sc-364432A
sc-364432B
sc-364432C
sc-364432D
5 mg
50 mg
100 mg
500 mg
1 g
$150.00
$1050.00
$1665.00
$3329.00
$4382.00
1
(1)

BI 2536 is a Plk1 inhibitor, which can lead to mitotic arrest and affect the levels of proteins involved in mitosis.