The category of Mitotic Cells Activators encompasses a group of compounds or molecules that play a role in regulating or modulating the processes associated with mitosis, which is a critical stage of the cell cycle. Mitosis is the cellular process by which a single eukaryotic cell divides into two identical daughter cells, each with the same genetic information as the parent cell. It is a tightly regulated and highly coordinated series of events that involves the duplication and separation of chromosomes, ensuring the accurate distribution of genetic material to daughter cells. Mitotic Cells Activators are substances that can influence and impact various stages of mitosis, such as the initiation of mitotic entry, spindle formation, chromosome condensation, alignment, segregation, and cytokinesis.
These activators can have diverse effects on mitotic cells, including the acceleration or deceleration of cell division, the promotion of chromosome stability or instability, and the modulation of checkpoint mechanisms that monitor the fidelity of mitosis. Researchers use Mitotic Cells Activators to explore the intricate molecular and cellular processes underlying cell division and to dissect the signaling pathways and molecular players involved in mitosis regulation. Understanding how these activators function in mitotic cells is essential for gaining insights into fundamental biological processes, including tissue development, growth, repair, and maintenance, as well as for elucidating the molecular mechanisms that drive diseases associated with mitotic dysregulation, such as cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their disassembly, affecting mitotic spindle dynamics and potentially upregulating mitotic proteins. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine binds to tubulin, inhibiting microtubule assembly and thus impacting mitotic spindle proteins and cell division. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide inhibits DNA topoisomerase II, causing DNA damage and potentially influencing the expression of proteins in response to cell cycle checkpoints. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Aphidicolin is a specific inhibitor of DNA polymerase, which can arrest cells in the S-phase and indirectly affect mitotic protein expression. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate is a dihydrofolate reductase inhibitor, disrupting DNA synthesis and potentially affecting the regulation of the cell cycle and mitotic protein expression. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine is a CDK inhibitor, and by inhibiting these kinases, it can affect cell cycle progression and the expression of mitotic proteins. | ||||||
BI6727 | 755038-65-4 | sc-364432 sc-364432A sc-364432B sc-364432C sc-364432D | 5 mg 50 mg 100 mg 500 mg 1 g | $150.00 $1050.00 $1665.00 $3329.00 $4382.00 | 1 | |
BI 2536 is a Plk1 inhibitor, which can lead to mitotic arrest and affect the levels of proteins involved in mitosis. | ||||||