MIP-T3 Antibody (C-9): sc-166337
- MIP-T3 Antibody (C-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-29 at the N-terminus of MIP-T3 of human origin
- recommended for detection of MIP-T3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for MIP-T3 Antibody (C-9) for WB applications. This reagent is now offered in a bundle with MIP-T3 Antibody (C-9) (see ordering information below).
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MIP-T3 Antibody (C-9) is a mouse monoclonal IgG2a antibody that detects MIP-T3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MIP-T3 plays a crucial role in cellular signaling by interacting with TRAF3, a key protein in the tumor necrosis factor receptor (TNFR) superfamily signaling pathway, which regulates essential processes like cell proliferation, differentiation, and apoptosis. The interaction between MIP-T3 and TRAF3 is particularly significant as MIP-T3 involves the coiled-coil TRAF-N domain of TRAF3, facilitating the recruitment of TRAF3 to microtubules. This association underscores MIP-T3′s importance in maintaining the integrity of the cytoskeletal network and suggests a novel mechanism for the spatial regulation of TRAF3, potentially influencing downstream signaling pathways. MIP-T3′s ability to bind to taxol-stabilized microtubules and tubulin in vitro further highlights functional relevance in cellular dynamics. With versatile applications and critical role in cellular signaling, anti-MIP-T3 antibody (C-9) serves as an invaluable tool for researchers studying the intricate mechanisms of cell regulation and the TNFR superfamily.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-T3 Antibody (C-9) | sc-166337 | 200 µg/ml | $322.00 | |||
MIP-T3 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-540082 | 200 µg Ab; 10 µg BP | $361.00 | |||
MIP-T3 (C-9) Neutralizing Peptide | sc-166337 P | 100 µg/0.5 ml | $69.00 |