MIP-1β Antibody (3H3): sc-130330
- MIP-1β Antibody (3H3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against recombinant MIP-1β of human origin
- MIP-1 beta Antibody (3H3) is recommended for detection of MIP-1β of human origin by WB, IP and ELISA
- Anti-MIP-1 beta Antibody (3H3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MIP-1β Antibody (3H3) for WB applications. These reagents are now offered in bundles with MIP-1β Antibody (3H3) (see ordering information below).
MIP-1β Antibody (3H3) is a mouse monoclonal IgG1 kappa light chain antibody that detects MIP-1β of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MIP-1β (3H3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MIP-1β, a member of the C-C chemokine subfamily, plays a crucial role in the immune response by acting as a chemoattractant for monocytes and T cells, particularly CD4+ T lymphocytes, which are essential for orchestrating adaptive immunity. The selective attraction of naive CD4+ T cells by MIP-1β is significant, as MIP-1β helps to regulate the immune response during infections, including HIV. Research indicates that MIP-1β, along with MIP-1α and RANTES, is produced by CD8+ T cells and contributes to the control of HIV infection by releasing HIV-suppressive factors. The ability of MIP-1β to selectively recruit specific T cell populations underscores MIP-1β′s importance in both normal immune function and in the context of viral infections, making MIP-1β a valuable target for therapeutic interventions and research applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MIP-1β Antibody (3H3) References:
- MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines. | Dorner, BG., et al. 2002. Proc Natl Acad Sci U S A. 99: 6181-6. PMID: 11972057
- Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8. | Oliveira, SH., et al. 2002. J Leukoc Biol. 71: 1019-25. PMID: 12050188
- MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity. | Lillard, JW., et al. 2003. Blood. 101: 807-14. PMID: 12393512
- The human CC chemokine MIP-1beta dimer is not competent to bind to the CCR5 receptor. | Jin, H., et al. 2007. J Biol Chem. 282: 27976-83. PMID: 17644519
- Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. | Bozza, FA., et al. 2008. BMC Infect Dis. 8: 86. PMID: 18578883
- New Insights into the Pro-Inflammatory Activities of Ang1 on Neutrophils: Induction of MIP-1β Synthesis and Release. | Dumas, E., et al. 2016. PLoS One. 11: e0163140. PMID: 27632174
- Decreased macrophage inflammatory protein (MIP)-1α and MIP-1β increase the risk of developing nasopharyngeal carcinoma. | Yang, MJ., et al. 2018. Cancer Commun (Lond). 38: 7. PMID: 29764502
- The Effect of Methyl-Derivatives of Flavanone on MCP-1, MIP-1β, RANTES, and Eotaxin Release by Activated RAW264.7 Macrophages. | Kłósek, M., et al. 2024. Molecules. 29: PMID: 38792101
- Plasma concentrations of IL-6, MIP-1β, IP-10, and PTX-3 as predictors of the immunological response to antiretroviral treatment in people with HIV. | Mejías-Trueba, M., et al. 2024. Front Immunol. 15: 1447926. PMID: 39267754
- Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis. | O'Grady, NP., et al. 1999. J Infect Dis. 179: 136-41. PMID: 9841832
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-1β Antibody (3H3) | sc-130330 | 200 µg/ml | $316.00 | |||
MIP-1β Antibody (3H3): m-IgG Fc BP-HRP Bundle | sc-528729 | 200 µg Ab; 10 µg BP | $354.00 | |||
MIP-1β Antibody (3H3): m-IgGκ BP-HRP Bundle | sc-521209 | 200 µg Ab, 40 µg BP | $354.00 | |||
MIP-1β Antibody (3H3): m-IgG1 BP-HRP Bundle | sc-543097 | 200 µg Ab; 20 µg BP | $354.00 | |||
MIP-1β Antibody (3H3) AC | sc-130330 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MIP-1β Antibody (3H3) HRP | sc-130330 HRP | 200 µg/ml | $316.00 | |||
MIP-1β Antibody (3H3) FITC | sc-130330 FITC | 200 µg/ml | $330.00 | |||
MIP-1β Antibody (3H3) PE | sc-130330 PE | 200 µg/ml | $343.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 488 | sc-130330 AF488 | 200 µg/ml | $357.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 546 | sc-130330 AF546 | 200 µg/ml | $357.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 594 | sc-130330 AF594 | 200 µg/ml | $357.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 647 | sc-130330 AF647 | 200 µg/ml | $357.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 680 | sc-130330 AF680 | 200 µg/ml | $357.00 | |||
MIP-1β Antibody (3H3) Alexa Fluor® 790 | sc-130330 AF790 | 200 µg/ml | $357.00 |