MIER2 Antibody (A-7): sc-514519
- MIER2 Antibody (A-7) is a mouse monoclonal IgG1 κ MIER2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 5-23 at the N-terminus of MIER2 of human origin
- MIER2 Antibody (A-7) is recommended for detection of MIER2 of human origin by WB, IP, IF and ELISA
- Anti-MIER2 Antibody (A-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MIER2 Antibody (A-7) for WB applications. These reagents are now offered in bundles with MIER2 Antibody (A-7) (see ordering information below).
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MIER2 Antibody (A-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects MIER2 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MIER2 antibody (A-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MIER2, or mesoderm induction early response 1, family member 2, is a 545 amino acid protein encoded by a gene located on human chromosome 19p13.3, which is notable for its high gene density and diverse array of important genes, including those linked to various diseases. MIER2 plays a crucial role in regulating gene expression during early embryonic development and is involved in mesodermal differentiation, making MIER2 essential for proper tissue formation and organogenesis. Understanding MIER2 function is vital, as dysregulation can lead to developmental disorders and contribute to various pathologies. MIER2 presence in specific cellular compartments, such as the nucleus, further underscores MIER2′s importance in transcriptional regulation and cellular signaling pathways. Using MIER2 (A-7) monoclonal antibody in your research can provide valuable insights into the mechanisms of development and disease associated with this critical protein.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MIER2 Antibody (A-7) References:
- C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers. | Wang, L., et al. 2000. Clin Cancer Res. 6: 2988-93. PMID: 10955775
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome. | Le Meur, N., et al. 2004. Eur J Hum Genet. 12: 415-8. PMID: 14970844
- Comparative human-mouse-rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q. | Leeb, T. and Müller, M. 2004. Gene. 343: 239-44. PMID: 15588578
- The extended human leukocyte receptor complex: diverse ways of modulating immune responses. | Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
- Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. | Olsen, A., et al. 1994. Genomics. 23: 659-68. PMID: 7851895
- The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family. | Teglund, S., et al. 1994. Genomics. 23: 669-84. PMID: 7851896
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIER2 Antibody (A-7) | sc-514519 | 200 µg/ml | $322.00 | |||
MIER2 Antibody (A-7): m-IgG Fc BP-HRP Bundle | sc-527912 | 200 µg Ab; 10 µg BP | $361.00 | |||
MIER2 Antibody (A-7): m-IgG1 BP-HRP Bundle | sc-533285 | 200 µg Ab; 20 µg BP | $361.00 | |||
MIER2 Antibody (A-7) AC | sc-514519 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MIER2 Antibody (A-7) HRP | sc-514519 HRP | 200 µg/ml | $322.00 | |||
MIER2 Antibody (A-7) FITC | sc-514519 FITC | 200 µg/ml | $336.00 | |||
MIER2 Antibody (A-7) PE | sc-514519 PE | 200 µg/ml | $349.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 488 | sc-514519 AF488 | 200 µg/ml | $364.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 546 | sc-514519 AF546 | 200 µg/ml | $364.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 594 | sc-514519 AF594 | 200 µg/ml | $364.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 647 | sc-514519 AF647 | 200 µg/ml | $364.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 680 | sc-514519 AF680 | 200 µg/ml | $364.00 | |||
MIER2 Antibody (A-7) Alexa Fluor® 790 | sc-514519 AF790 | 200 µg/ml | $364.00 | |||
MIER2 (A-7) Neutralizing Peptide | sc-514519 P | 100 µg/0.5 ml | $69.00 |